FlyBase (flybase. org) is a knowledge base that supports the community of researchers that
use the fruit fly, Drosophila melanogaster, as a model organism. The FlyBase team curates …

In this review, we discuss the current status and future challenges for fully elucidating the
fungal tree of life. In the last 15 years, advances in genomic technologies have …

OrthoDB provides evolutionary and functional annotations of genes in a diverse sampling of
eukaryotes, prokaryotes, and viruses. Genomics continues to accelerate our exploration of …

Genomics drives the current progress in molecular biology, generating unprecedented
volumes of data. The scientific value of these sequences depends on the ability to evaluate …

Rational protein engineering requires a holistic understanding of protein function. Here, we
apply deep learning to unlabeled amino-acid sequences to distill the fundamental features …

OrthoVenn is a powerful web platform for the comparison and analysis of whole-genome
orthologous clusters. Here we present an updated version, OrthoVenn2, which provides new …

Abstract OrthoDB (https://www. orthodb. org) provides evolutionary and functional
annotations of orthologs. This update features a major scaling up of the resource coverage …

Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly
changing technologies and expanding data volumes make evaluation of completeness a …

Phylogenomic studies using genome-scale amounts of data have greatly improved
understanding of the tree of life. Despite the diversity, ecological significance, and …

OMA is an established resource to elucidate evolutionary relationships among genes from
currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise …