Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Background Critically ill patients routinely receive antibiotics with activity against anaerobic
gut bacteria. However, in other disease states and animal models, gut anaerobes are …

The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …

The production of peptides and small proteins with microbicidal activity collectively called
antimicrobial peptides (AMPs) is commonly considered to be a primitive mechanism of …

Hospital-acquired pneumonia and ventilator-associated pneumo... : Current Opinion in
Pulmonary Medicine Hospital-acquired pneumonia and ventilator-associated pneumonia …

Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped
early for benefit (truncated RCTs) systematically overestimate treatment effects for the …

Context Ventilator-associated pneumonia (VAP) causes substantial morbidity. A silver-
coated endotracheal tube has been designed to reduce VAP incidence by preventing …