Objectives Glioma is one of the most aggressive brain tumours with poor overall survival
despite advanced technology in surgical resection, chemotherapy and radiation …

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor
survival. Cytoreduction in association with radiotherapy and temozolomide (TMZ) is the …

Malignant pleural mesothelioma (MPM) is a rare tumor with an extremely poor prognosis. Its
pathogenesis is related to an immune response against asbestos fibers. The T-lymphocytes …

Simple Summary Glioblastoma is a rapidly progressing brain cancer that is very difficult to
treat. Given that many aspects of cell and tissue behavior are controlled by electric signaling …

Abstract Background The V-ATPase proton pump controls acidification of intra and extra-
cellular milieu in both physiological and pathological conditions. We previously showed that …

Glioblastoma is a highly malignant cancer with no effective treatment. It is vital to elucidate
the mechanisms which drive glioblastoma in order to identify therapeutic targets. The …

Aberrant expression of coding genes of the V-ATPase subunits has been reported in glioma
patients that can activate oncogenic pathways and result in worse prognosis. However, the …

Background V-ATPases are hetero-oligomeric enzymes consisting of 13 subunits and
playing key roles in ion homeostasis and signaling. Differential expression of these proton …

Simple Summary The epigenetic state within cells represents a layer for controlling
homeostasis and cell differentiation. In cancer, this fine-tuned program is disrupted, resulting …

A percentage of celiac disease (CD) patients develop refractory type-2 disease (RCD2), a
condition associated with increased risk of enteropathy-associated T-cell-lymphoma (EATL) …