We present a survey of recent advancements in the emerging field of patient-specific
modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue …

Insertion of a microelectrode into the brain to record/stimulate neurons damages neural
tissue and blood vessels and initiates the brain's wound healing response. Due to the large …

Objective. Brain tissue undergoes dramatic molecular and cellular remodeling at the implant–
tissue interface that evolves over a period of weeks after implantation. The biomechanical …

Characterizing the dynamic mechanical properties of brain tissue is deemed important for
developing a comprehensive knowledge of the mechanisms underlying brain injury. The …

The mechanical properties of human brain tissue are the subject of interest because of their
use in understanding brain trauma and in developing therapeutic treatments and …

The smooth surface structure of intracortical microelectrodes implanted within the nanometer‐
scale architecture of brain tissue may contribute to the foreign body response. Here, the …

In this paper the human brain tissue constitutive model for monotonic loading is developed.
The model in this work is based on the anisotropic hyperelasticity assumption (the …

Cell distribution and nutrient supply in 3D cell-laden hydrogel scaffolds are critical and
should mimic the in vivo cellular environment, but been difficult to control with conventional …

Despite significant progress in understanding the disease mechanism of traumatic brain
injury (TBI), promising preclinical therapeutics have seldom been translated into successful …

Purpose. During brain tumor surgery, planning and guidance are based on preoperative
images which do not account for brain-shift. However, this deformation is a major source of …