Acne is the most common skin disorder. In the majority of cases, acne is a disease that
changes its skin distribution and severity over time; moreover, it can be a physically (scar …

Acne, one of the most common skin disorders, is also a cardinal component of many
systemic diseases or syndromes. Their association illustrates the nature of these diseases …

Although the complement system is centrally involved in host defense, its overactivation or
deregulation (eg, due to inherent host genetic defects or due to pathogen subversion) may …

As specific autoimmune disorders now constitute established risk factors for malignant
lymphomas, we describe this association. We review reported risk levels, risk determinants …

There are a number of systemic disorders that can manifest with urticarial skin lesions,
including urticarial vasculitis, connective tissue diseases, hematologic diseases, and …

Urticaria is often classified as acute, chronic, or physical based on duration of symptoms and
the presence or absence of inducing stimuli. Urticarial vasculitis, contact urticaria, and …

Autoinflammatory diseases include disorders with a monogenic cause and also complex
conditions associated to polygenic or multifactorial factors. An increased number of both …

Sarcoidosis is characterized by intense inflammation at the different sites of localization.
Many different mediators, such as cytokines, chemokines, and other proteins with various …

We have found a B2 repeat insertion in the gene encoding protein tyrosine phosphatase
nonreceptor type 6 (PTPN6) in a mouse that developed a skin disorder with clinical and …

Autoinflammatory diseases encompass a group of inflammatory diseases that are non‐
infectious, non‐allergic, non‐autoimmune and non‐immunodeficient. The term was initially …