Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview
AA Hamidi, G Khalili-Tanha, Z Nasrpour Navaei… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the second most common cause of cancer mortality and a major
health challenge worldwide. Despite advances in therapeutic and diagnostic methods, there …
health challenge worldwide. Despite advances in therapeutic and diagnostic methods, there …
Pharmacological modulation of ubiquitin-proteasome pathways in oncogenic signaling
The ubiquitin-proteasome pathway (UPP) is involved in regulating several biological
functions, including cell cycle control, apoptosis, DNA damage response, and apoptosis. It is …
functions, including cell cycle control, apoptosis, DNA damage response, and apoptosis. It is …
Ovarian cancer stem cells and targeted therapy
Background Ovarian cancer has the highest ratio of mortality among gynecologic
malignancies. Chemotherapy is one of the most common treatment options for ovarian …
malignancies. Chemotherapy is one of the most common treatment options for ovarian …
MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer
Thyroid cancer (TC) is one of the most frequent endocrine malignancies that is more
common among females. Tumor recurrence is one of the most important clinical …
common among females. Tumor recurrence is one of the most important clinical …
MicroRNAs as the critical regulators of Doxorubicin resistance in breast tumor cells
Background Chemotherapy is one of the most common treatment options for breast cancer
(BC) patients. However, about half of the BC patients are chemotherapeutic resistant …
(BC) patients. However, about half of the BC patients are chemotherapeutic resistant …
TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma
SA Khales, S Mozaffari-Jovin, D Geerts… - BMC cancer, 2022 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers
worldwide. Overexpression of EMT master transcription factors can promote differentiated …
worldwide. Overexpression of EMT master transcription factors can promote differentiated …
Molecular interactions of miR-338 during tumor progression and metastasis
M Moghbeli - Cellular & molecular biology letters, 2021 - Springer
Background Cancer, as one of the main causes of human deaths, is currently a significant
global health challenge. Since the majority of cancer-related deaths are associated with late …
global health challenge. Since the majority of cancer-related deaths are associated with late …
MicroRNA-377: A therapeutic and diagnostic tumor marker
Cancer is considered as one of the main causes of human deaths globally. Despite the
recent progresses in therapeutic modalities, there is still a high rate of mortality among …
recent progresses in therapeutic modalities, there is still a high rate of mortality among …
Targeting crosstalk of signaling pathways in cancer stem cells: a promising approach for development of novel anti-cancer therapeutics
S Bhal, CN Kundu - Medical Oncology, 2023 - Springer
Abstract Wnt, Hedgehog (Hh), and Notch signaling pathways are the evolutionarily
conserved signaling pathways that regulate the embryonic development and also play …
conserved signaling pathways that regulate the embryonic development and also play …
Comprehending the crosstalk between Notch, Wnt and Hedgehog signaling pathways in oral squamous cell carcinoma-clinical implications
Background Oral squamous cell carcinoma (OSCC) is a malignant oral cavity neoplasm that
affects many people, especially in developing countries. Despite several advances that have …
affects many people, especially in developing countries. Despite several advances that have …