[HTML][HTML] Molecular characterization of the meq gene of Marek's disease viruses detected in unvaccinated backyard chickens reveals the circulation of low-and high …

G Mescolini, C Lupini, V Felice, A Guerrini, F Silveira… - Poultry Science, 2019 - Elsevier
Marek's disease (MD) is an important lymphoproliferative disease of chickens, caused by
Gallid alphaherpesvirus 2 (GaHV-2). Outbreaks are commonly reported in commercial …

Molecular characterization and phylogenetic analysis of marek's disease virus in Iran

A Ghalyanchilangeroudi, H Hosseini… - Avian …, 2022 - meridian.allenpress.com
Marek's disease (MD) is a highly contagious, lymphoproliferative poultry disease caused by
the oncogenic herpesvirus, serotype 1 Marek's disease virus (MDV-1), or Gallid herpesvirus …

The emergence of a vv+ MDV can break through the protections provided by the current vaccines

M Shi, M Li, W Wang, Q Deng, Q Li, Y Gao, P Wang… - Viruses, 2020 - mdpi.com
Marek's disease (MD) is an infectious malignant T-cell lymphoma proliferative disease
caused by Marek's disease virus (MDV). In recent years, the emergence of very virulent (vv) …

Intrahost speciations and host switches played an important role in the evolution of herpesviruses

AF Brito, G Baele, KD Nahata, ND Grubaugh… - Virus …, 2021 - academic.oup.com
In times when herpesvirus genomic data were scarce, the cospeciation between these
viruses and their hosts was considered to be common knowledge. However, as more …

Genetic characterization of Marek's disease virus in chickens in Thailand reveals a high genetic diversity of circulating strains

S Wannaratana, W Tunterak… - Transboundary and …, 2022 - Wiley Online Library
Marek's disease (MD) is a highly contagious lymphoproliferative disease of chickens caused
by Gallid alphaherpesvirus 2, commonly known as serotype 1 Marek's disease virus (MDV …

Marek's disease viruses circulating in commercial poultry in Italy in the years 2015–2018 are closely related by their meq gene phylogeny

G Mescolini, C Lupini, I Davidson… - Transboundary and …, 2020 - Wiley Online Library
Marek's disease (MD) is a lymphoproliferative disease important to the poultry industry
worldwide; it is caused by Gallid alphaherpesvirus 2 (GaHV‐2). The virulence of GaHV‐2 …

An overview on marek's disease virus evolution and evidence for increased virulence in brazil

ACD Torres, SY Marin, CS Costa… - Brazilian Journal of …, 2019 - SciELO Brasil
Marek's disease virus (MDV) has been shown to be evolving to higher virulence. One of the
genetic sites involved in virulence which enables such characterization is the 339-amino …

Genetic characterization of a Marek's disease virus strain isolated in Japan

S Murata, Y Machida, M Isezaki, N Maekawa… - Virology journal, 2020 - Springer
Background Marek's disease virus (MDV) causes malignant lymphomas in chickens
(Marek's disease, MD). MD is currently controlled by vaccination; however, MDV strains …

Marek's disease virus activates the PI3K/akt pathway through interaction of its protein meq with the P85 subunit of PI3K to promote viral replication

H Li, J Zhu, M He, Q Luo, F Liu, R Chen - Frontiers in Microbiology, 2018 - frontiersin.org
It is known that viruses can active the phosphatidylinositol 3-kinase (PI3K)/Akt signaling
pathway in host cells to support cell survival and viral replication; however, the role of …

Newly detected mutations in the Meq oncogene and molecular pathotyping of very virulent Marek's disease herpesvirus in Tunisia

J Lachheb, H Mastour, J Nsiri, K Kaboudi, I Choura… - Archives of …, 2020 - Springer
Marek's disease (MD) is a contagious avian viral disease that is responsible for large
economic losses to farmers. The disease is caused by Marek's disease virus (species Gallid …