[PDF][PDF] Synthesis, Pharmacological Evaluation, and In-Silico Studies of Thiophene Derivatives.
The relevance of Retinoic acid receptor-related orphan receptors in cancer progression has
sparked interest in developing multifunctional therapeutics. In the search for potentially …
sparked interest in developing multifunctional therapeutics. In the search for potentially …
Antifungal activity of topical microemulsion containing a thiophene derivative
GP Guimarães, MYFA Reis, DTC Silva… - Brazilian Journal of …, 2014 - SciELO Brasil
Fungal infections have become a major problem of worldwide concern. Yeasts belonging to
the Candida genus and the pathogenic fungus Cryptococcus neoformans are responsible …
the Candida genus and the pathogenic fungus Cryptococcus neoformans are responsible …
Evaluation of the antiproliferative activity of 2-amino thiophene derivatives against human cancer cells lines
ACV of Aguiar, RO of Moura, JFBM Junior… - Biomedicine & …, 2016 - Elsevier
In spite of great progress in understanding cancer biology, current therapeutic procedures
remain unsatisfactory. Chemotherapy is often followed by secondary effects with cellular …
remain unsatisfactory. Chemotherapy is often followed by secondary effects with cellular …
Investigation of the effects of plasma-treated chitosan electrospun fibers onto biofilm formation
This work describes the synthesis and characterization of new plasma-treated chitosan
derivatives for the prevention of the biofilm formation of Pseudomonas aeruginosa PA01 (P …
derivatives for the prevention of the biofilm formation of Pseudomonas aeruginosa PA01 (P …
Synthesis of tetrahydrobenzo [b] thiophene-3-carbohydrazide derivatives as potential anti-cancer agents and Pim-1 kinase inhibitors
RM Mohareb, WW Wardakhan… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: Tetrahydrobenzo [b] thiophene derivatives are well known to be biologically
active compounds and many of them occupy a wide range of anticancer agent drugs …
active compounds and many of them occupy a wide range of anticancer agent drugs …
Heterocyclization of 2-Arylidenecyclohexan-1, 3-dione: Synthesis of Thiophene, Thiazole, and Isoxazole Derivatives with Potential Antitumor Activities
NYM Abdo, RM Mohareb… - Anti-Cancer Agents in …, 2020 - ingentaconnect.com
Background: Thiophene, thiazole, and isoxazole derivatives are present in a wide range of
natural and synthetic compounds with heterogeneous pharmacological activity. Due to their …
natural and synthetic compounds with heterogeneous pharmacological activity. Due to their …
Reactions of ketene dithioacetal for a new versatile synthesis of 4, 5-substituted 3-aminothiophene-2-carboxylate derivatives
SM Chavan, RB Toche, VM Patil… - Journal of Sulfur …, 2016 - Taylor & Francis
Poly substituted 3-aminothiophenes were successfully synthesized in good yields by using a
one-pot protocol via ketene S, S-acetal as an intermediate in basic medium (K2CO3/N, N …
one-pot protocol via ketene S, S-acetal as an intermediate in basic medium (K2CO3/N, N …
Synthesis and characterization of blue fluorescent surface modified nano-graphene oxide flakes as a pH-sensitive drug delivery system
A new blue fluorescent surface modified graphene oxide (GO) by 6-(5-bromothiophen-2-yl)
benzo [c][1, 2, 5] selenadiazole-5-carboxylic acid (TB) denoted as (GO-TB) was synthesized …
benzo [c][1, 2, 5] selenadiazole-5-carboxylic acid (TB) denoted as (GO-TB) was synthesized …
The uses of cyclohexan-1, 4-dione for the synthesis of thiophene derivatives as new anti-proliferative, prostate anticancer, c-Met and tyrosine kinase inhibitors
RM Mohareb, F Al-Omran, RA Ibrahim - Medicinal Chemistry Research, 2018 - Springer
A series of heterocyclic compounds derived from the dihydrobenzo [b] thiophene derivatives
were synthesized all the synthesized compounds were determined by elemental analysis, 1 …
were synthesized all the synthesized compounds were determined by elemental analysis, 1 …
5CN05 partitioning in an aqueous two-phase system: A new approach to the solubilization of hydrophobic drugs
AM Lopes, V de Carvalho Santos-Ebinuma… - Process …, 2014 - Elsevier
Liquid–liquid extraction for the purification of molecules has been central to many advances
in the pharmaceutical industry. These processes were developed based on the property that …
in the pharmaceutical industry. These processes were developed based on the property that …