Machine learning strategies in microRNA research: bridging genome to phenome

S Daniel Thomas, K Vijayakumar, L John… - OMICS: A Journal of …, 2024 - liebertpub.com
MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

Computational resources for prediction and analysis of functional miRNA and their targetome

I Monga, M Kumar - Computational Biology of Non-Coding RNA: Methods …, 2019 - Springer
Abstract microRNAs are evolutionarily conserved, endogenously produced, noncoding
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …

GeneAI 3.0: powerful, novel, generalized hybrid and ensemble deep learning frameworks for miRNA species classification of stationary patterns from nucleotides

J Singh, NN Khanna, RK Rout, N Singh, JR Laird… - Scientific reports, 2024 - nature.com
Due to the intricate relationship between the small non-coding ribonucleic acid (miRNA)
sequences, the classification of miRNA species, namely Human, Gorilla, Rat, and Mouse is …

Computational methods for predicting mature microRNAs

M Yousef, A Parveen, A Kumar - miRNomics: MicroRNA Biology and …, 2022 - Springer
Tiny single-stranded noncoding RNAs with size 19–27 nucleotides serve as microRNAs
(miRNAs), which have emerged as key gene regulators in the last two decades. miRNAs …

Improving classification of mature microRNA by solving class imbalance problem

Y Wang, X Li, B Tao - Scientific reports, 2016 - nature.com
Abstract MicroRNAs (miRNAs) are~ 20–25 nucleotides non-coding RNAs, which regulated
gene expression in the post-transcriptional level. The accurate rate of identifying the start sit …

Adaboost-SVM-based probability algorithm for the prediction of all mature miRNA sites based on structured-sequence features

Y Wang, J Ru, Y Jiang, J Zhang - Scientific reports, 2019 - nature.com
The significant role of microRNAs (miRNAs) in various biological processes and diseases
has been widely studied and reported in recent years. Several computational methods …

An approach to identify individual functional single nucleotide polymorphisms and isoform MicroRNAs

Y Wang, J Ru, T Jin, M Sun, L Jia… - BioMed Research …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) and single nucleotide polymorphisms (SNPs) play important roles in
disease risk and development, especially cancer. Importantly, when SNPs are located in pre …

GeneAI 3.0: Powerful, Novel, Generalized Hybrid and Ensemble Deep Learning Frameworks for miRNA Classification of species-specific Stationary Patterns from …

J Singh, NN Khanna, RK Rout, N Singh, JR Laird… - 2023 - researchsquare.com
Abstract Background and Motivation: Due to the intricate relationship between the small non-
coding ribonucleic acid (miRNA) sequences, the classification of miRNA species, namely …

[HTML][HTML] 利用基因表达值相对大小秩序标志鉴别肺癌

燕花陈, 宝童郑, 云轻林, 慧敏朱, 智军郑… - Sheng Wu Yi Xue …, 2017 - ncbi.nlm.nih.gov
在应用基于转录组特征构建的支持向量机、 贝叶斯分类器等传统分类器对组织样本进行分类时,
要求对基因表达谱进行样本间的数据标准化处理, 以去除实验批次效应带来的影响 …

A signature based on relative gene expression orderings for lung cancer diagnosis

Y Chen, B Zheng, Y Lin, H Zhu, Z Zheng… - Sheng wu yi xue …, 2017 - europepmc.org
在应用基于转录组特征构建的支持向量机, 贝叶斯分类器等传统分类器对组织样本进行分类时,
要求对基因表达谱进行样本间的数据标准化处理, 以去除实验批次效应带来的影响 …