Epicardial adipose tissue in contemporary cardiology

G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …

Epicardial adipose tissue and cardiovascular diseases

AM Ansaldo, F Montecucco, A Sahebkar… - International journal of …, 2019 - Elsevier
Obesity is a heterogeneous disease with different degrees of cardiovascular (CV) and
metabolic manifestations. Certain ectopic fat depots may contribute to obesity-related CV …

Role of epicardial adipose tissue in cardiovascular diseases: a review

M Konwerski, A Gąsecka, G Opolski, M Grabowski… - Biology, 2022 - mdpi.com
Simple Summary Cardiovascular diseases (CVDs) are the leading causes of death
worldwide. Epicardial adipose tissue (EAT) is one of the most important risk factors for …

Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease

VB Patel, S Shah, S Verma, GY Oudit - Heart failure reviews, 2017 - Springer
Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …

ACE2 deficiency worsens epicardial adipose tissue inflammation and cardiac dysfunction in response to diet-induced obesity

VB Patel, J Mori, BA McLean, R Basu, SK Das… - Diabetes, 2016 - Am Diabetes Assoc
Obesity is increasing in prevalence and is strongly associated with metabolic and
cardiovascular disorders. The renin-angiotensin system (RAS) has emerged as a key …

Physical activity, fitness, and obesity in heart failure with preserved ejection fraction

A Pandey, KV Patel, M Vaduganathan, S Sarma… - JACC: Heart Failure, 2018 - jacc.org
Heart failure with preserved ejection fraction (HFpEF) is common, increasing in prevalence,
and refractory to available pharmacotherapies. Our understanding of HFpEF has evolved …

Inflammation in metabolic cardiomyopathy

FA Wenzl, S Ambrosini, SA Mohammed… - Frontiers in …, 2021 - frontiersin.org
Overlapping pandemics of lifestyle-related diseases pose a substantial threat to
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …

Role of epicardial adipose tissue in health and disease: a matter of fat?

B Gaborit, C Sengenes, P Ancel, A Jacquier… - Comprehensive …, 2017 - hal.science
Epicardial adipose tissue (EAT) is a small but very biologically active ectopic fat depot that
surrounds the heart. Given its rapid metabolism, thermogenic capacity, unique …

Pericardial, but not hepatic, fat by CT is associated with CV outcomes and structure: the multi-ethnic study of atherosclerosis

RV Shah, A Anderson, J Ding, M Budoff, O Rider… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The study sought to determine the associations between local (pericardial) fat
and incident cardiovascular disease (CVD) events and cardiac remodeling independent of …

The ratio between visceral and subcutaneous abdominal fat assessed by computed tomography is an independent predictor of mortality and cardiac events

R Ladeiras-Lopes, F Sampaio, N Bettencourt… - Revista Española de …, 2017 - Elsevier
Introduction and objectives Obesity is an important cardiovascular risk factor and the
location of fat deposits seems to be an important determinant of its metabolic impact …