Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

Peripheral nerve injury is normally followed by a robust regenerative response. Here we
describe the early changes associated with injury from the initial rise in intracellular calcium …

Unlike its central counterpart, the peripheral nervous system is well known for its
comparatively good potential for regeneration following nerve fiber injury. This ability is …

Classic mechanisms of tumor response to chemotherapy include apoptosis, mitotic
catastrophe. Recent studies have suggested that cellular senescence, a terminal …

The transition from the proinflammatory phase to the prohealing phase in wound healing is
essential for effective skin wound repair, which involves the balance of M1 and M2 …

Gastric cancer (GC) is one of the most common malignancies and its prognosis is extremely
poor. This study identifies a novel oncogene, microfibrillar-associated protein 2 (MFAP2) in …

Trauma in the adult mammalian central nervous system leads to irreversible structural and
functional impairment due to failed regeneration attempts. In contrast, neurons in the …

Thyroid hormone (TH) regulates many cellular events underlying perinatal brain
development in vertebrates. Whether and how TH regulates brain development when neural …

Objective This study aimed to define the role of interleukine-1β (IL-1β) and tumor necrosis
factor-α (TNF-α) in the expression of P311 in vascular endothelial cells (VECs) and in wound …

P311, a gene that was identified in 1993, has been found to have diverse biological
functions in processes such as cell proliferation, migration and differentiation. However, its …