[HTML][HTML] Physiological changes due to hepatotoxicity and the protective role of some medicinal plants
HS Abou Seif - Beni-suef University journal of basic and applied …, 2016 - Elsevier
The liver is the largest, important organ and the site for essential biochemical reactions in
the human body. It has the function to detoxify toxic substances and synthesize useful …
the human body. It has the function to detoxify toxic substances and synthesize useful …
A review of the hepatoprotective effects of hesperidin, a flavanon glycoside in citrus fruits, against natural and chemical toxicities
Objectives Liver is the most important and functional organ in the body to metabolize and
detoxify endogenous compounds and xenobiotics. The major goal of the present narrative …
detoxify endogenous compounds and xenobiotics. The major goal of the present narrative …
Rutin and Quercetin Counter Doxorubicin‐Induced Liver Toxicity in Wistar Rats via Their Modulatory Effects on Inflammation, Oxidative Stress, Apoptosis, and Nrf2
The presented study was performed to verify whether rutin and/or quercetin can inhibit liver
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …
Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer
Despite advances in cancer treatment modalities, DNA still stands as one of the targets for
anticancer agents. DNA minor groove binders (MGBs) represent an important investigational …
anticancer agents. DNA minor groove binders (MGBs) represent an important investigational …
Quercetin and naringenin abate diethylnitrosamine/acetylaminofluorene-induced hepatocarcinogenesis in Wistar rats: the roles of oxidative stress, inflammation and …
This study was designed to assess the preventive effects and to suggest the probable
mechanisms of action of quercetin and naringein in diethylnitrosamine (DEN)/2 …
mechanisms of action of quercetin and naringein in diethylnitrosamine (DEN)/2 …
Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …
[HTML][HTML] Cerium oxide nanoparticles: In pursuit of liver protection against doxorubicin-induced injury in rats
HG Ibrahim, N Attia, AH Fatma El Zahraa… - Biomedicine & …, 2018 - Elsevier
Doxorubicin (DOX) is considered as a backbone in several chemotherapeutic regimens.
Nevertheless, the reported systemic toxicity usually hampers its broad application …
Nevertheless, the reported systemic toxicity usually hampers its broad application …
Artemisia annua Extract Attenuate Doxorubicin-Induced Hepatic Injury via PI-3K/Akt/Nrf-2-Mediated Signaling Pathway in Rats
Doxorubicin (DOX), which is used to treat cancer, has harmful effects that limit its therapeutic
application. Finding preventative agents to thwart DOX-caused injuries is thus imperative …
application. Finding preventative agents to thwart DOX-caused injuries is thus imperative …
Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats
P Patel, J Shah - Life Sciences, 2021 - Elsevier
Abstract Aims Doxorubicin (Dox) is routinely used for breast cancer treatment but toxicity and
drug resistance limit its use. The objective of the study was to investigate the protective …
drug resistance limit its use. The objective of the study was to investigate the protective …
Hepatoprotective effects of Alpinia officinarum rhizome extract on cisplatin-induced hepatotoxicity in rats: A biochemical, histopathological and immunohistochemical …
F Niazvand, A Ashtari, N Chamkouri, M Azari - Journal of Trace Elements in …, 2023 - Elsevier
Background Alpinia officinarum is a member of the ginger family (Zingiberaceae), which is
widely cultivated in Asia and traditionally used for its anti-inflammatory, antimicrobial, and …
widely cultivated in Asia and traditionally used for its anti-inflammatory, antimicrobial, and …