Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome

BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Review of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: an evidence-based approach to diagnosis and management by clinicians

AC Bested, LM Marshall - Reviews on Environmental Health, 2015 - degruyter.com
This review was written from the viewpoint of the treating clinician to educate health care
professionals and the public about Myalgic Encephalomyelitis/Chronic Fatigue Syndrome …

Myalgic encephalomyelitis/chronic fatigue syndrome diagnosis and management in young people: a primer

PC Rowe, RA Underhill, KJ Friedman, A Gurwitt… - Frontiers in …, 2017 - frontiersin.org
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease that
affects children and adolescents as well as adults. The etiology has not been established …

Differences in excitatory and inhibitory neurotransmitter levels between depressed patients and healthy controls: a systematic review and meta-analysis

KEM Godfrey, AC Gardner, S Kwon, W Chea… - Journal of psychiatric …, 2018 - Elsevier
Dysfunction of gamma-aminobutyric acid (GABA) and/or glutamate neurotransmitter systems
have increasingly been implicated in the aetiology of Major Depressive Disorder (MDD). It …

[HTML][HTML] Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome

Ø Fluge, O Mella, O Bruland, K Risa, SE Dyrstad… - JCI insight, 2016 - ncbi.nlm.nih.gov
Myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) is a debilitating disease of
unknown etiology, with hallmark symptoms including postexertional malaise and poor …

Fecal microbiota transplantation: a new therapeutic attempt from the gut to the brain

HM Xu, HL Huang, YL Zhou, HL Zhao… - Gastroenterology …, 2021 - Wiley Online Library
Gut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal
microbiota transplantation (FMT) is a biological therapy that entails transferring the gut …

Neuroinflammation and cytokines in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a critical review of research methods

MB VanElzakker, SA Brumfield… - Frontiers in neurology, 2019 - frontiersin.org
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is the label given to a
syndrome that can include long-term flu-like symptoms, profound fatigue, trouble …

[HTML][HTML] Plasma metabolomics reveals disrupted response and recovery following maximal exercise in myalgic encephalomyelitis/chronic fatigue syndrome

A Germain, L Giloteaux, GE Moore, SM Levine… - JCI insight, 2022 - ncbi.nlm.nih.gov
Post-exertional malaise (PEM) is a hallmark symptom of myalgic encephalomyelitis/chronic
fatigue syndrome (ME/CFS). We monitored the evolution of 1157 plasma metabolites in 60 …

[HTML][HTML] The pathobiology of myalgic encephalomyelitis/chronic fatigue syndrome: the case for neuroglial failure

H Renz-Polster, ME Tremblay, D Bienzle… - Frontiers in cellular …, 2022 - frontiersin.org
Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and
distinctive profile of clinical features, the disease remains an enigma because causal …