Recent progress in the treatment of cancer in children

E Butler, K Ludwig, HL Pacenta… - CA: a cancer journal …, 2021 - Wiley Online Library
Although significant improvements have been made in the outcomes of children with cancer,
the pace of improvement has slowed in recent years as the limits of therapy intensification …

[HTML][HTML] ACCELERATE–Five years accelerating cancer drug development for children and adolescents

ADJ Pearson, SL Weiner, PC Adamson… - European Journal of …, 2022 - Elsevier
Rapid evaluation and subsequent regulatory approval of new drugs are critical to improving
survival and reducing long-term side-effects for children and adolescents with cancer. The …

Nivolumab and brentuximab vedotin with or without bendamustine for R/R Hodgkin lymphoma in children, adolescents, and young adults

P Harker-Murray, C Mauz-Körholz… - Blood, The Journal …, 2023 - ashpublications.org
Children, adolescents, and young adults (CAYA) with relapsed/refractory (R/R) classic
Hodgkin lymphoma (cHL) without complete metabolic response (CMR) before autologous …

Brentuximab vedotin in combination with chemotherapy for pediatric patients with ALK+ ALCL: results of COG trial ANHL12P1

EJ Lowe, AF Reilly, MS Lim, TG Gross… - Blood, The Journal …, 2021 - ashpublications.org
Approximately 30% of pediatric patients with anaplastic large cell lymphoma (ALCL)
relapse. Although brentuximab vedotin has demonstrated excellent activity in ALCL, it has …

[HTML][HTML] Targeted inhibitors and antibody immunotherapies: Novel therapies for paediatric leukaemia and lymphoma

E Brivio, A Baruchel, A Beishuizen, JP Bourquin… - European Journal of …, 2022 - Elsevier
Despite improved outcomes achieved in the last decades for children with newly diagnosed
leukaemia and lymphoma, treatment of patients with refractory/relapsed disease remains a …

Childhood, adolescent and young adult non‐Hodgkin lymphoma: current perspectives

MS Cairo, A Beishuizen - British journal of haematology, 2019 - Wiley Online Library
Summary The 6th International Symposium on Childhood, Adolescent and Young Adult
(CAYA) Non‐Hodgkin Lymphoma (NHL) was held in Rotterdam, Netherlands, 26–29 …

Stem cell transplantation and vinblastine monotherapy for relapsed pediatric anaplastic large cell lymphoma: results of the international, prospective ALCL-relapse …

F Knörr, L Brugières, M Pillon… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To analyze the efficacy of a risk-stratified treatment of children with relapsed
anaplastic large cell lymphoma (ALCL). The ALCL-Relapse trial (ClinicalTrials. gov …

Diagnosis and management of Hodgkin lymphoma in children, adolescents, and young adults

JA Belsky, J Hochberg, L Giulino-Roth - Best Practice & Research Clinical …, 2023 - Elsevier
Advances in the management of Hodgkin lymphoma in children, adolescents and young
adult have resulted in survival outcomes exceeding 90%. The risk of late toxicity, however …

Transplant-free approach in relapsed Hodgkin lymphoma in children, adolescents, and young adults: a nonrandomized clinical trial

S Daw, PD Cole, BS Hoppe, D Hodgson… - JAMA …, 2025 - jamanetwork.com
Importance Retrieval strategies for children, adolescents, and young adults with relapsed
classic Hodgkin lymphoma (cHL) aim to maintain efficacy while minimizing long-term toxic …

Risk and response adapted treatment guidelines for managing first relapsed and refractory classical Hodgkin lymphoma in children and young people …

S Daw, D Hasenclever, M Mascarin… - …, 2020 - journals.lww.com
The objective of this guideline is to aid clinicians in making individual salvage treatment
plans for pediatric and adolescent patients with first relapse or refractory (R/R) classical …