X Du, TY Pang - Frontiers in psychiatry, 2015 - frontiersin.org
There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …
CL Chuang, F Demontis - Ageing research reviews, 2021 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disease that is caused by expansion of cytosine/adenosine/guanine repeats in the huntingtin (HTT) gene …
Unlike many other neurodegenerative diseases with established gene–environment interactions, Huntington's disease (HD) is viewed as a disorder governed by genetics. The …
E Bruzelius, J Scarpa, Y Zhao, S Basu… - Movement …, 2019 - Wiley Online Library
Background Despite extensive research regarding the etiology of Huntington's disease, relatively little is known about the epidemiology of this rare disorder, particularly in the …
RE Hokenson, AK Short, Y Chen, AL Pham… - Journal of …, 2021 - Soc Neuroscience
Stress may promote emotional and cognitive disturbances, which differ by sex. Adverse outcomes, including memory disturbances, are typically observed following chronic stress …
Background The glymphatic system has recently been proposed to function as a brain-wide macroscopic system for the clearance of potentially harmful molecules, such as amyloid beta …
CE Lyons, A Bartolomucci - Neuroscience & biobehavioral reviews, 2020 - Elsevier
Chronic stress has been shown to promote numerous aging-related diseases, and to accelerate the aging process itself. Of particular interest is the impact of stress on …
Neurodegenerative diseases are a great concern because of aging worldwide population. Despite substantial effort to advance our understanding of the etiology and potential …
Alzheimer's Disease (AD) is the most prevalent progressive neurodegenerative disease; to date, no AD therapy has proven effective in delaying or preventing the disease course. In the …