Natural killer (NK) cells are part of the innate immune defense against infection and cancer
and are especially useful in combating certain viral pathogens. The utility of NK cells in …

Lysosome‐related organelles (LROs) comprise a diverse group of cell type‐specific,
membrane‐bound subcellular organelles that derive at least in part from the endolysosomal …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

Human NK cells are innate immune effectors that play a critical roles in the control of viral
infection and malignancy. The importance of their homeostasis and function can be …

Hermansky–Pudlak syndrome (HPS) is a group of 10 autosomal recessive multisystem
disorders, each defined by the deficiency of a specific gene. HPS‐associated genes encode …

Background Primary immunodeficiency (PID) disorders are a heterogeneous group of
inherited disorders caused by a variety of monogenetic immune defects. Thus far, mutations …

Hermansky-Pudlak syndrome (HPS) is an autosomal recessive disorder associated with
highly penetrant pulmonary fibrosis in young adults with subtypes HPS-1, HPS-2, and HPS …

Abstract Purpose Hermansky–Pudlak syndrome (HPS) is characterized by oculocutaneous
albinism, excessive bleeding, and often additional symptoms. Variants in ten different genes …

H ermansky–P udlak syndrome (HPS) is an autosomal recessive and genetically
heterogeneous disorder characterized by oculocutaneous albinism, bleeding tendency, and …

The characterization of primary immunodeficiencies (PIDs) in human subjects is crucial for a
better understanding of the biology of the immune response. New achievements in this field …