Mammalian target of rapamycin (mTOR) is a highly conserved Serine/Threonine (Ser/Thr)
protein kinase, which belongs to phosphatidylinositol-3-kinase-related kinase (PIKK) protein …

Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …

Sirt1 is the most prominent and extensively studied member of sirtuins, the family of
mammalian class III histone deacetylases heavily implicated in health span and longevity …

The average lifespan of humans is increasing, and with it the percentage of people entering
the 65 and older age group is growing rapidly and will continue to do so in the next 20 years …

Resveratrol has emerged in recent years as a compound conferring strong protection
against metabolic, cardiovascular and other age-related complications, including …

Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors
and the onset and consolidation of dementia and Alzheimer's disease (AD). It has been …

Resveratrol (RSV) is a natural polyphenol that has a beneficial effect on health, and
resveratrol-induced autophagy has been suggested to be a key process in mediating many …

Acne vulgaris is an epidemic inflammatory disease of the human sebaceous follicle and
represents the most common skin disease affecting about 85% of adolescents in …

Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a polyphenol phytoalexin present in a
variety of plant species and has been implicated to explain the health benefits of red wine. A …

Ageing is associated with the functional decline of all tissues and a striking increase in many
diseases. Although ageing has long been considered a one-way street, strategies to delay …