Antigen-specific immune reactions to ischemic stroke

X Urra, F Miró, A Chamorro, AM Planas - Frontiers in cellular …, 2014 - frontiersin.org
Brain proteins are detected in the cerebrospinal fluid (CSF) and blood of stroke patients and
their concentration is related to the extent of brain damage. Antibodies against brain …

Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity

T Vogl, M Eisenblätter, T Völler, S Zenker… - Nature …, 2014 - nature.com
Inflammation has a key role in the pathogenesis of various human diseases. The early
detection, localization and monitoring of inflammation are crucial for tailoring individual …

Chloride co‐transporters as possible therapeutic targets for stroke

MAS Martín‐Aragón Baudel, AV Poole… - Journal of …, 2017 - Wiley Online Library
Stroke is one of the major causes of death and disability worldwide. The major type of stroke
is an ischaemic one, which is caused by a blockage that interrupts blood flow to the brain …

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated …

B Wang, Y Liu, L Huang, J Chen, JJ Li, R Wang… - Molecular …, 2017 - nature.com
Induction of neuroprotective heat-shock proteins via pharmacological Hsp90 inhibitors is
currently being investigated as a potential treatment for neurodegenerative diseases. Two …

Neuronal PirB upregulated in cerebral ischemia acts as an attractive theranostic target for ischemic stroke

J Wang, Y Zhang, J Xia, T Cai, J Du… - Journal of the …, 2018 - Am Heart Assoc
Background Ischemic stroke is a complex disease with multiple etiologies and clinical
manifestations. Paired immunoglobulin‐like receptor B (PirB), which is originally thought to …

Combination of MRI‐Guided High‐Intensity Focused Ultrasound and Bioluminescent Biological Systems to Assess Thermal Therapies for Tumor and Tumor …

P Jeanjean, D El Hamrani, C Genevois… - Advanced Materials …, 2022 - Wiley Online Library
This work presents an integrated technology for assessing in vivo anticancer treatments in
mice, based on various heating conditions. Bioluminescence imaging (BLI) is used to …

Electroporation-Induced Stress Response and Its Effect on Gene Electrotransfer Efficacy: In Vivo Imaging and Numerical Modeling

T Forjanič, B Markelc, M Marčan… - IEEE Transactions …, 2019 - ieeexplore.ieee.org
Objective: Skin is an attractive target tissue for gene transfer due to its size, accessibility, and
its immune competence. One of the promising delivery methods is gene delivery by means …

Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat

IS Dhande, SC Kneedler, Y Zhu, AS Joshi, MJ Hicks… - Genes & …, 2020 - nature.com
Similar to humans, the risk of cerebrovascular disease in stroke-prone spontaneously
hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the …

A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector

R Buj, N Iglesias, AM Planas, T Santalucia - BMC molecular biology, 2013 - Springer
Background Valuable clone collections encoding the complete ORFeomes for some model
organisms have been constructed following the completion of their genome sequencing …

Dual-reporter in vivo imaging of transient and inducible heat-shock promoter activation

PY Fortin, C Genevois, M Chapolard… - Biomedical Optics …, 2014 - opg.optica.org
Gene promoter activity can be studied in vivo by molecular imaging methods using reporter
gene technology. Transcription of the reporter and the reported genes occurs …