Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …

Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …

Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for
significant mortality and morbidity worldwide. The genus comprises more than seventy …

Dengue virus (DENV) is the mosquito-borne virus of greatest human health concern. There
are four serotypes of DENV (1-4) that co-circulate in endemic areas. Each serotype of DENV …

Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use
of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human …

In 2019, the United States Food and Drug Administration accorded restricted approval to
Sanofi Pasteur's Dengvaxia, a live attenuated vaccine (LAV) for dengue fever, a mosquito …

In presently licensed vaccines, killed or attenuated organisms act as a source of
immunogens except for peptide-based vaccines. These conventional vaccines required a …

Hepatitis B remains one of the major global health problems more than 40 years after the
identification of human hepatitis B virus (HBV) as the causative agent. A critical turning point …

Flaviviruses such as dengue, yellow fever, Zika, West Nile, and Japanese encephalitis virus
present substantial global health burdens. New vaccines are being sought to address safety …

Dengue virus (DENV) consists of four serotypes in the family Flaviviridae and is a causative
agent of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. DENV is …