DSF-family quorum sensing signal-mediated intraspecies, interspecies, and inter-kingdom communication
While most bacteria are unicellular microbes they communicate with each other and with
their environments to adapt their behaviors. Quorum sensing (QS) is one of the best-studied …
their environments to adapt their behaviors. Quorum sensing (QS) is one of the best-studied …
The DSF family of quorum sensing signals: diversity, biosynthesis, and turnover
The diffusible signaling factor (DSF)-based quorum sensing (QS) system has emerged as a
widely conserved cell–cell communication mechanism in Gram-negative bacteria. Typically …
widely conserved cell–cell communication mechanism in Gram-negative bacteria. Typically …
A Pseudomonas aeruginosa small RNA regulates chronic and acute infection
The ability to switch between different lifestyles allows bacterial pathogens to thrive in
diverse ecological niches,. However, a molecular understanding of their lifestyle changes …
diverse ecological niches,. However, a molecular understanding of their lifestyle changes …
Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms
Bacterial biofilms present a significant medical challenge because they are recalcitrant to
current therapeutic regimes. A key component of biofilm formation in the opportunistic …
current therapeutic regimes. A key component of biofilm formation in the opportunistic …
What's on the outside matters: the role of the extracellular polymeric substance of Gram-negative biofilms in evading host immunity and as a target for therapeutic …
JS Gunn, LO Bakaletz, DJ Wozniak - Journal of Biological Chemistry, 2016 - ASBMB
Biofilms are organized multicellular communities encased in an extracellular polymeric
substance (EPS). Biofilm-resident bacteria resist immunity and antimicrobials. The EPS …
substance (EPS). Biofilm-resident bacteria resist immunity and antimicrobials. The EPS …
Control of Biofilms with the Fatty Acid Signaling Molecule cis-2-Decenoic Acid
Biofilms are complex communities of microorganisms in organized structures attached to
surfaces. Importantly, biofilms are a major cause of bacterial infections in humans, and …
surfaces. Importantly, biofilms are a major cause of bacterial infections in humans, and …
Going beyond the control of quorum-sensing to combat biofilm infections
WR Abraham - Antibiotics, 2016 - mdpi.com
Most bacteria attach to surfaces where they form a biofilm, cells embedded in a complex
matrix of polymers. Cells in biofilms are much better protected against noxious agents than …
matrix of polymers. Cells in biofilms are much better protected against noxious agents than …
Identification of genes involved in enhanced membrane vesicle formation in Pseudomonas aeruginosa biofilms: surface sensing facilitates vesiculation
M Kanno, T Shiota, S Ueno, M Takahara… - Frontiers in …, 2023 - frontiersin.org
Membrane vesicles (MVs) are small spherical structures (20–400 nm) produced by most
bacteria and have important biological functions including toxin delivery, signal transfer …
bacteria and have important biological functions including toxin delivery, signal transfer …
Small Is Mighty—Chemical Communication Systems in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of acute and
chronic infections. Usually a commensal on the host body, P. aeruginosa is capable of …
chronic infections. Usually a commensal on the host body, P. aeruginosa is capable of …
Diffusible signal factor‐dependent quorum sensing in pathogenic bacteria and its exploitation for disease control
JM Dow - Journal of Applied Microbiology, 2017 - academic.oup.com
Cell‐to‐cell signals of the diffusible signal factor (DSF) family are cis‐2‐unsaturated fatty
acids of differing chain length and branching pattern. DSF signalling has been described in …
acids of differing chain length and branching pattern. DSF signalling has been described in …