The Renoprotective Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i)—A Narrative Review

L Iordan, L Gaita, R Timar, V Avram, A Sturza… - International Journal of …, 2024 - mdpi.com
Chronic kidney disease (CKD) is a noncommunicable condition that has become a major
healthcare burden across the globe, often underdiagnosed and associated with low …

Hypoglycemic activity of Garcinia mangostana L. extracts on diabetes rodent models: A systematic review and network meta-analysis

M Chatatikun, A Tedasen, P Phinyo… - Frontiers in …, 2024 - frontiersin.org
Background Diabetes mellitus is a significant global health issue, and alternative treatments
from natural products like Garcinia mangostana L.[Clusiaceae] or GM are being explored for …

Prevalence of peripheral neuropathy, amputation, and quality of life in patients with diabetes mellitus

W Perveen, H Ahsan, R Shahzad, S Fayyaz, A Zaif… - Scientific Reports, 2024 - nature.com
Peripheral neuropathy and amputation are common complications of diabetes mellitus (DM)
that significantly impact the quality of life of the affected individuals. This study aims to …

[HTML][HTML] Exploring the efficacy of alpha-lipoic acid in Comorbid Osteoarthritis and Type 2 diabetes Mellitus

I Halabitska, V Oksenych, O Kamyshnyi - Nutrients, 2024 - mdpi.com
Background/Objectives. The comorbidity of osteoarthritis and type 2 diabetes mellitus poses
a complex clinical challenge, complicating patient management due to overlapping …

Explainable deep learning for diabetes diagnosis with DeepNetX2

SA Tanim, TE Shrestha, MDRI Emon, MF Mridha… - … Signal Processing and …, 2025 - Elsevier
Diabetes is a leading health global health challenge because of its high blood sugar levels
and the risk of extensive damage to other internal organs. Early and accurate identification …

Design, Synthesis, and Biological Evaluation of 1, 4-Dihydropyridine–Indole as a Potential Antidiabetic Agent via GLUT4 Translocation Stimulation

S Katiyar, S Ahmad, A Kumar, A Ansari… - Journal of Medicinal …, 2024 - ACS Publications
In the quest for the discovery of antidiabetic compounds, a series of 27 1, 4-dihydropyridine–
indole derivatives were synthesized using a diversity approach. These compounds were …

Integrative metabolomics and chemometrics depict the metabolic alterations of differently processed red kidney beans (Phaseolus vulgaris L.) and in relation to in-vitro …

DS Ghallab, DA Ghareeb, DA Goda - Food Research International, 2024 - Elsevier
Red kidney beans (RKB) serve as a powerhouse packed with a plethora of largely
unexplored extraordinary chemical entities with potential significance. However, their …

[HTML][HTML] Leveraging Shapley Additive Explanations for Feature Selection in Ensemble Models for Diabetes Prediction

PK Mohanty, SAJ Francis, RK Barik, DS Roy, MJ Saikia - Bioengineering, 2024 - mdpi.com
Diabetes, a significant global health crisis, is primarily driven in India by unhealthy diets and
sedentary lifestyles, with rapid urbanization amplifying these effects through convenience …

Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?

A Kowluru - Biochemical Pharmacology, 2023 - Elsevier
It is widely accepted that pancreatic islet β-cell failure and the onset of type 2 diabetes
(T2DM) constitute an intricate interplay between the genetic expression of the disease and a …

Sweet or sour? A review of the Aspartame market landscape, carcinogenicity, and its socioeconomic impact

H Sharma, A Hilal, GK Aseri, N Jain - Journal of Food Science and …, 2024 - Springer
Artificial sweeteners with almost zero calories are in high demand in the food and beverage
industries due to an increase in diabetes and obesity cases throughout the globe. They vary …