Formins in human disease

L Labat-de-Hoz, MA Alonso - Cells, 2021 - mdpi.com
Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …

The formin Fmn2b is required for the development of an excitatory interneuron module in the zebrafish acoustic startle circuit

D Nagar, TK James, R Mishra, S Guha, SM Burgess… - Eneuro, 2021 - eneuro.org
The formin family member Fmn2 is a neuronally enriched cytoskeletal remodeling protein
conserved across vertebrates. Recent studies have implicated Fmn2 in neurodevelopmental …

Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching

T Kundu, SS Das, LK Sewatkar, DS Kumar… - Journal of …, 2022 - Soc Neuroscience
Interstitial collateral branching of axons is a critical component in the development of
functional neural circuits. Axon collateral branches are established through a series of …

Convergent evolution on oceanic islands: comparative genomics reveals species-specific processes in birds

M Recuerda, JCH Montoya, G Blanco… - Authorea …, 2024 - advance.sagepub.com
Understanding the factors driving phenotypic and genomic differentiation of insular
populations is of major interest to gain insight into the speciation process. Comparing …

Development of motor neurons and motor activity in zebrafish requires F-actin nucleation by Fmn2b

D Nagar, B Carrington, SM Burgess, A Ghose - bioRxiv, 2021 - biorxiv.org
Background Cytoskeletal remodelling plays a pivotal role in the establishment of neuronal
connectivity during development and in plasticity in adults. Mutations in the cytoskeleton …

Formin-2b (Fmn2b) in the development of neural circuits in zebrafish

D Nagar - 2021 - dr.iiserpune.ac.in
The formin family member, Fmn2, is a neuronally enriched cytoskeletal remodelling protein
conserved across vertebrates. Recent studies have implicated Fmn2 in neurodevelopmental …

Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency

J Li, T Peng, L Wang, P Long, R Quan, H Tan… - Journal of Ovarian …, 2022 - Springer
Background Premature ovarian insufficiency (POI) plagues 1% of women under 40, while
quite a few remain an unknown cause. The development of sequencing has helped find …

[引用][C] Nuclear actin assembly is required for chromatin reorganization after mitosis as well as androgen receptor signaling

J Knerr - 2024 - Dissertation, Universität Freiburg …