[HTML][HTML] Artificial intelligence and early detection of pancreatic cancer: 2020 summative review

B Kenner, ST Chari, D Kelsen, DS Klimstra, SJ Pandol… - Pancreas, 2021 - journals.lww.com
Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …

Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention

EM Stoffel, RE Brand, M Goggins - Gastroenterology, 2023 - Elsevier
Pancreatic cancer usually results in poor survival with limited options for treatment, as most
affected individuals present with advanced disease. Early detection of preinvasive …

[HTML][HTML] Timeline of development of pancreatic cancer and implications for successful early detection in high-risk individuals

KA Overbeek, MG Goggins, M Dbouk, IJM Levink… - Gastroenterology, 2022 - Elsevier
Background & Aims To successfully implement imaging-based pancreatic cancer (PC)
surveillance, understanding the timeline and morphologic features of neoplastic progression …

Screening for pancreatic cancer has the potential to save lives, but is it practical?

BL Mazer, JW Lee, NJ Roberts, LC Chu… - Expert Review of …, 2023 - Taylor & Francis
Introduction Most patients with pancreatic cancer present with advanced stage, incurable
disease. However, patients with high-grade precancerous lesions and many patients with …

Radiomics-based machine-learning models can detect pancreatic cancer on prediagnostic computed tomography scans at a substantial lead time before clinical …

S Mukherjee, A Patra, H Khasawneh, P Korfiatis… - Gastroenterology, 2022 - Elsevier
Background & Aims Our purpose was to detect pancreatic ductal adenocarcinoma (PDAC)
at the prediagnostic stage (3–36 months before clinical diagnosis) using radiomics-based …

Fully automatic deep learning framework for pancreatic ductal adenocarcinoma detection on computed tomography

N Alves, M Schuurmans, G Litjens, JS Bosma… - Cancers, 2022 - mdpi.com
Simple Summary Early image-based diagnosis is crucial to improve outcomes in pancreatic
ductal adenocarcinoma (PDAC) patients, but is challenging even for experienced …

CT abnormalities of the pancreas associated with the subsequent diagnosis of clinical stage I pancreatic ductal adenocarcinoma more than 1 year later: a case-control …

F Toshima, R Watanabe, D Inoue… - American Journal of …, 2021 - Am Roentgen Ray Soc
Please see the Editorial Comment by Neeraj Lalwani discussing this article. To listen to the
podcast associated with this article, please select one of the following: iTunes, Google Play …

[HTML][HTML] Early detection initiative: a randomized controlled trial of algorithm-based screening in patients with new onset hyperglycemia and diabetes for early detection …

ST Chari, A Maitra, LM Matrisian, EE Shrader… - Contemporary clinical …, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is the only leading cause of cancer death
without an early detection strategy. In retrospective studies, 0.5–1% of subjects> 50 years of …

Automated artificial intelligence model trained on a large data set can detect pancreas cancer on diagnostic computed tomography scans as well as visually occult …

P Korfiatis, G Suman, NG Patnam, KH Trivedi… - Gastroenterology, 2023 - Elsevier
Background & Aims The aims of our case-control study were (1) to develop an automated 3-
dimensional (3D) Convolutional Neural Network (CNN) for detection of pancreatic ductal …

[HTML][HTML] Focal pancreatic parenchyma atrophy is a harbinger of pancreatic cancer and a clue to the intraductal spreading subtype

J Nakahodo, M Kikuyama, Y Fukumura, S Horiguchi… - Pancreatology, 2022 - Elsevier
Abstract Background/Objectives Radiological evidence of focal pancreatic parenchymal
atrophy (FPPA) may presage early pancreatic ductal adenocarcinoma (PDAC) development …