[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
The phospholipase A2 superfamily as a central hub of bioactive lipids and beyond
M Murakami - Pharmacology & therapeutics, 2023 - Elsevier
Abstract In essence,“phospholipase A 2”(PLA 2) means a group of enzymes that release
fatty acids and lysophospholipids by hydrolyzing the sn-2 position of glycerophospholipids …
fatty acids and lysophospholipids by hydrolyzing the sn-2 position of glycerophospholipids …
Segregated functions of two cytosolic phospholipase A2 isoforms (cPLA2α and cPLA2ε) in lipid mediator generation
M Murakami, R Takamiya, Y Miki, N Sugimoto… - Biochemical …, 2022 - Elsevier
Among the phospholipase A 2 (PLA 2) superfamily, group IVA cytosolic PLA 2 (cPLA 2 α) is
currently attracting much attention as a central regulator of arachidonic acid (AA) metabolism …
currently attracting much attention as a central regulator of arachidonic acid (AA) metabolism …
Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti‐inflammatory lipid N‐acylethanolamine
L Liang, R Takamiya, Y Miki, K Heike… - The FASEB …, 2022 - Wiley Online Library
Psoriasis is an inflammatory disorder characterized by keratinocyte hyper‐proliferation and
Th17‐type immune responses. However, the roles of bioactive lipids and the regulation of …
Th17‐type immune responses. However, the roles of bioactive lipids and the regulation of …
Deciphering complex interactions in bioactive lipid signaling
M Maccarrone - Molecules, 2023 - mdpi.com
Lipids are usually viewed as metabolic fuel and structural membrane components. Yet, in
recent years, different families of lipids able to act as authentic messengers between cells …
recent years, different families of lipids able to act as authentic messengers between cells …
[引用][C] Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
An update on Glycerophosphodiester Phosphodiesterases; From Bacteria to Human
The hydrolysis of deacylated glycerophospholipids into sn-glycerol 3-phosphate and alcohol
is facilitated by evolutionarily conserved proteins known as glycerophosphodiester …
is facilitated by evolutionarily conserved proteins known as glycerophosphodiester …
PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis
MM Sikder, S Sasaki, Y Miki, Y Nagasaki, K Ohta… - … et Biophysica Acta (BBA …, 2025 - Elsevier
N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and
appetite-suppressive activities. Among them, palmitoylethanolamide (PEA) and …
appetite-suppressive activities. Among them, palmitoylethanolamide (PEA) and …
[HTML][HTML] Перспективы фармакологического применения N-ацилэтаноламинов полиненасыщенных жирных кислот в терапии заболеваний органов дыхания на …
ИС Коваленко, ЮК Денисенко… - … и патологии дыхания, 2022 - cyberleninka.ru
Введение. В настоящее время не до конца изучены и механизмы процессов
разрешения хронического воспаления при бронхиальной астме (БА). Требуется поиск …
разрешения хронического воспаления при бронхиальной астме (БА). Требуется поиск …
Tribute to Professor Raphael Mechoulam, The Founder of Cannabinoid and Endocannabinoid Research
M Maccarrone - Molecules, 2022 - mdpi.com
During the last 60 years the relevance for human health and disease of cannabis (Cannabis
sativa or Cannabis indica) ingredients, like the psychoactive compound A9 …
sativa or Cannabis indica) ingredients, like the psychoactive compound A9 …