Key Points Frailty in Older Adults Assessing frailty enables clinicians to predict the outcomes
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …

Background Frailty is increasingly recognized as an important construct which has health
implications for older adults. The Clinical Frailty Scale (CFS) is a judgement-based frailty …

This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …

Background The COVID-19 pandemic has placed unprecedented strain on health-care
systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the …

Background Physical frailty and sarcopenia show extensive clinical similarities. Whether
biomarkers exist that are shared by the two conditions is presently unclear. Methods We …

Delphi is a scientific method to organize and structure an expert discussion aiming to
generate insights on controversial topics with limited information. The technique has seen a …

The ability to investigate therapeutic interventions in animal models of neurodegenerative
diseases depends on extensive characterization of the model (s) being used. There are …

Eight years have passed since the publication of the only guideline on cardiac rehabilitation
(CR) in Japan,“Guidelines for rehabilitation in patients with cardiovascular disease (JCS …

Abstract Background in 2010, the European Working Group on Sarcopenia in Older People
(EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying …

“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …