Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models

S Caddeo, M Boffito, S Sartori - Frontiers in bioengineering and …, 2017 - frontiersin.org
In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined
to develop bioartificial substitutes for organs and tissues, which can in turn be applied in …

Nanotopography-guided tissue engineering and regenerative medicine

HN Kim, A Jiao, NS Hwang, MS Kim, DH Kim… - Advanced drug delivery …, 2013 - Elsevier
Human tissues are intricate ensembles of multiple cell types embedded in complex and well-
defined structures of the extracellular matrix (ECM). The organization of ECM is frequently …

Advanced cell culture platforms: a growing quest for emulating natural tissues

M Mirbagheri, V Adibnia, BR Hughes… - Materials …, 2019 - pubs.rsc.org
In the body, cells inhabit within a complex three-dimensional (3D) extracellular matrix that
provides physical and chemical signals to regulate the cell fate. Cultured cells in Petri dishes …

25th anniversary article: scalable multiscale patterned structures inspired by nature: the role of hierarchy

WG Bae, HN Kim, D Kim, SH Park… - Advanced …, 2014 - Wiley Online Library
Multiscale, hierarchically patterned surfaces, such as lotus leaves, butterfly wings, adhesion
pads of gecko lizards are abundantly found in nature, where microstructures are usually …

In vitro cardiac tissue models: current status and future prospects

A Mathur, Z Ma, P Loskill, S Jeeawoody… - Advanced drug delivery …, 2016 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Achieving the next phase
of potential treatment strategies and better prognostic tools will require a concerted effort …

Development of miniaturized walking biological machines

V Chan, K Park, MB Collens, H Kong, TA Saif… - Scientific reports, 2012 - nature.com
The quest to 'forward-engineer'and fabricate biological machines remains a grand
challenge. Towards this end, we have fabricated locomotive “bio-bots” from hydrogels and …

Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery

SM Willerth, SE Sakiyama-Elbert - StemJournal, 2019 - content.iospress.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Harnessing localized ridges for high‐aspect‐ratio hierarchical patterns with dynamic tunability and multifunctionality

C Cao, HF Chan, J Zang, KW Leong… - Advanced …, 2014 - Wiley Online Library
Topographical patterns are of fundamental importance to materials science, physics,
chemistry and biology, impacting applications as diverse as antifouling, microfluidic device …

Patterning methods for polymers in cell and tissue engineering

HN Kim, DH Kang, MS Kim, A Jiao, DH Kim… - Annals of biomedical …, 2012 - Springer
Polymers provide a versatile platform for mimicking various aspects of physiological
extracellular matrix properties such as chemical composition, rigidity, and topography for …