Applications of deep learning techniques for automated multiple sclerosis detection using magnetic resonance imaging: A review

A Shoeibi, M Khodatars, M Jafari, P Moridian… - Computers in Biology …, 2021 - Elsevier
Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor
problems for people with a detrimental effect on the functioning of the nervous system. In …

Dose calculation algorithms for external radiation therapy: an overview for practitioners

F De Martino, S Clemente, C Graeff, G Palma, L Cella - Applied sciences, 2021 - mdpi.com
Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

Decreasing brain iron in multiple sclerosis: The difference between concentration and content in iron MRI

F Schweser, J Hagemeier, MG Dwyer… - Human brain …, 2021 - Wiley Online Library
Increased brain iron concentration is often reported concurrently with disease development
in multiple sclerosis (MS) and other neurodegenerative diseases. However, it is unclear …

Stratification of multiple sclerosis patients using unsupervised machine learning: a single-visit MRI-driven approach

G Pontillo, S Penna, S Cocozza, M Quarantelli… - European …, 2022 - Springer
Objectives To stratify patients with multiple sclerosis (pwMS) based on brain MRI-derived
volumetric features using unsupervised machine learning. Methods The 3-T brain MRIs of …

Neuroimaging correlates of cognitive dysfunction in adults with multiple sclerosis

M Petracca, G Pontillo, M Moccia, A Carotenuto… - Brain Sciences, 2021 - mdpi.com
Cognitive impairment is a frequent and meaningful symptom in multiple sclerosis (MS),
caused by the accrual of brain structural damage only partially counteracted by effective …

Unraveling deep gray matter atrophy and iron and myelin changes in multiple sclerosis

G Pontillo, M Petracca, S Monti… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Modifications of magnetic susceptibility have been
consistently demonstrated in the subcortical gray matter of MS patients, but some …

Magnetic resonance imaging in primary progressive multiple sclerosis patients

M Siger - Clinical Neuroradiology, 2022 - Springer
The recently developed effective treatment of primary progressive multiple sclerosis (PPMS)
requires the accurate diagnosis of patients with this type of disease. Currently, the diagnosis …

Clinical correlates of R1 relaxometry and magnetic susceptibility changes in multiple sclerosis: a multi-parameter quantitative MRI study of brain iron and myelin

G Pontillo, M Petracca, S Monti, M Quarantelli… - European …, 2023 - Springer
Objectives The clinical impact of brain microstructural abnormalities in multiple sclerosis
(MS) remains elusive. We aimed to characterize the topography of longitudinal relaxation …

Lesion volume in relapsing multiple sclerosis is associated with perivascular space enlargement at the level of the basal ganglia

SC Kolbe, LM Garcia, N Yu… - American Journal …, 2022 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Perivascular spaces surround the blood vessels of the
brain and are involved in neuroimmune functions and clearance of metabolites via the …

A combined radiomics and machine learning approach to overcome the clinicoradiologic paradox in multiple sclerosis

G Pontillo, S Tommasin, R Cuocolo… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Conventional MR imaging explains only a fraction of the
clinical outcome variance in multiple sclerosis. We aimed to evaluate machine learning …