Nephroprotective activity of medicinal plants: A review on in silico-, in vitro-, and in vivo-based studies

D Sujana, NM Saptarini, SA Sumiwi… - Journal of Applied …, 2021 - japsonline.com
Acute kidney injury (AKI) is a severe problem for healthcare professionals due to its high
mortality rate. The major causes of AKI are ischemia, hypoxia, and drug-induced …

Natural medicines for acute renal failure: A review

M Boozari, H Hosseinzadeh - Phytotherapy research, 2017 - Wiley Online Library
Acute renal failure (ARF) is a life‐threating disease with high mortality percentage. Two
important mechanisms of ARF are inflammation and oxidative stress. Plants are rich source …

[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles protect against acute kidney injury through anti-oxidation by enhancing Nrf2/ARE activation in rats

G Zhang, X Zou, Y Huang, F Wang, S Miao… - Kidney and Blood …, 2016 - karger.com
Background/Aims: Anti-oxidation is an effective strategy for curing acute kidney injury (AKI).
Herein, we suggest that extracellular vesicles (EVs) derived from mesenchymal stromal cells …

Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress

AM Soliman, S Desouky, M Marzouk, AA Sayed - Nutrients, 2016 - mdpi.com
Despite the fact that cisplatin is an important anticancer drug, its clinical utilization is limited
by nephrotoxicity during long term medication. Combined cisplatin chemotherapy with plant …

Protective effect of dendropanoxide against cadmium-induced hepatotoxicity via anti-inflammatory activities in Sprague-Dawley rats

S Gali, S Sharma, A Kundu, E Lee, JH Han… - Toxicology …, 2023 - Taylor & Francis
Cadmium (Cd) accumulates in the body through contaminated foods or water and causes
pathological damage to the liver via oxidative stress and inflammatory reactions. This study …

Aqueous Extract of Dendropanax morbiferus Leaves Effectively Alleviated Neuroinflammation and Behavioral Impediments in MPTP‐Induced Parkinson's Mouse …

SY Park, G Karthivashan, HM Ko… - Oxidative medicine …, 2018 - Wiley Online Library
Parkinson's disease (PD) is a commonly reported age‐related neurodegenerative disorder.
Microglial‐mediated neuroinflammation is one of the cardinal hallmarks of various …

Potent anti-inflammatory and analgesic actions of the chloroform extract of Dendropanax morbifera mediated by the Nrf2/HO-1 pathway

M Akram, KA Kim, ES Kim, AS Syed, CY Kim… - Biological and …, 2016 - jstage.jst.go.jp
Dendropanax morbifera LEVEILLE (DP) has been used in traditional Korean medicines to
treat a variety of inflammatory diseases. Although the in vitro anti-inflammatory potential of …

[HTML][HTML] Evaluation of vitamin C supplementation on kidney function and vascular reactivity following renal ischemic injury in mice

YB Zhu, YP Zhang, J Zhang, YB Zhang - Kidney and Blood Pressure …, 2016 - karger.com
Background/Aims: Renal ischemia/reperfusion injury (IRI) is a very common clinical event
and usually leads to ischemic acute renal failure (ARF). In the present study, we investigated …

Dendropanax morbiferus and other species from the genus Dendropanax: therapeutic potential of its traditional uses, phytochemistry, and pharmacology

R Balakrishnan, DY Cho, I Su-Kim, DK Choi - Antioxidants, 2020 - mdpi.com
The Dendropanax genus is a kind of flowering plant in the family of Araliaceae that
encompasses approximately 91 to 95 species. Several Dendropanax species are used as …

Antioxidant effects of Dendropanax morbifera Léveille extract in the hippocampus of mercury-exposed rats

W Kim, DW Kim, DY Yoo, HY Jung, JW Kim… - … and alternative medicine, 2015 - Springer
Background Dendropanax morbifera Léveille has been employed for the treatment of
infectious diseases using folk medicine. In this study, we evaluated the antioxidant effects of …