The implications of categorical and category-free mixed selectivity on representational geometries

MT Kaufman, MK Benna, M Rigotti, F Stefanini… - Current opinion in …, 2022 - Elsevier
The firing rates of individual neurons displaying mixed selectivity are modulated by multiple
task variables. When mixed selectivity is nonlinear, it confers an advantage by generating a …

New insights on single-neuron selectivity in the era of population-level approaches

FE Vaccari, S Diomedi, M Filippini… - Frontiers in Integrative …, 2022 - frontiersin.org
In the past, neuroscience was focused on individual neurons seen as the functional units of
the nervous system, but this approach fell short over time to account for new experimental …

Concurrent-and after-effects of medial temporal lobe stimulation on directed information flow to and from prefrontal and parietal cortices during memory formation

A Das, V Menon - Journal of Neuroscience, 2023 - Soc Neuroscience
Electrical stimulation of the medial temporal lobe (MTL) has the potential to uncover causal
circuit mechanisms underlying memory function. However, little is known about how MTL …

Effects of ketamine on frontoparietal interactions in a rule-based antisaccade task in macaque monkeys

L Ma, N Katyare, K Johnston, S Everling - Journal of Neuroscience, 2024 - jneurosci.org
Cognitive control is engaged by working memory processes and high-demand situations
like antisaccade, where one must suppress a prepotent response. While it is known to be …

Is the Dorsolateral Prefrontal Cortex Actually Several Different Brain Areas?

A Ahuja, NY Rodriguez - Journal of Neuroscience, 2022 - Soc Neuroscience
The human dorsolateral prefrontal cortex (DLPFC) has long captured the attention of
neuroscientists because of the diversity of the cognitive functions it supports. Its involvement …

Shared neural activity but distinct neural dynamics for cognitive control in monkey prefrontal and parietal cortex

RK Blackman, DA Crowe, AL DeNicola… - Journal of …, 2023 - Soc Neuroscience
To better understand how prefrontal networks mediate forms of cognitive control disrupted in
schizophrenia, we translated a variant of the AX continuous performance task that measures …

Don't Cut Corners: Exact Conditions for Modularity in Biologically Inspired Representations

W Dorrell, K Hsu, L Hollingsworth, JH Lee, J Wu… - arXiv preprint arXiv …, 2024 - arxiv.org
Why do biological and artificial neurons sometimes modularise, each encoding a single
meaningful variable, and sometimes entangle their representation of many variables? In this …

Domain general frontoparietal regions show modality-dependent coding of auditory and visual rules

JB Jackson, ANB Rich, D Moerel, L Teichmann… - bioRxiv, 2024 - biorxiv.org
A defining feature of human cognition is our ability to respond flexibly to what we see and
hear, changing how we respond depending on our current goals. In fact, we can rapidly …

Spontaneously emerging internal models of visual sequences combine abstract and event-specific information in the prefrontal cortex

ME Bellet, M Gay, J Bellet, B Jarraya, S Dehaene… - Cell Reports, 2024 - cell.com
When exposed to sensory sequences, do macaque monkeys spontaneously form abstract
internal models that generalize to novel experiences? Here, we show that neuronal …

Visual perceptual learning of feature conjunctions leverages non-linear mixed selectivity

B Karami, CM Schwiedrzik - npj Science of Learning, 2024 - nature.com
Visual objects are often defined by multiple features. Therefore, learning novel objects
entails learning feature conjunctions. Visual cortex is organized into distinct anatomical …