Understanding extracellular vesicle and nanoparticle heterogeneity: Novel methods and considerations

W Phillips, E Willms, AF Hill - Proteomics, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous population of membrane‐enclosed
nanoparticles released by cells. They play a role in intercellular communication and are …

The roles of exosomal immune checkpoint proteins in tumors

C Xing, H Li, RJ Li, L Yin, HF Zhang, ZN Huang… - Military Medical …, 2021 - Springer
Targeting immune checkpoints has achieved great therapeutic effects in the treatment of
early-stage tumors. However, most patients develop adaptive resistance to this therapy. The …

Mass spectrometry-based proteomics of human milk to identify differentially expressed proteins in women with breast cancer versus controls

R Aslebagh, D Whitham, D Channaveerappa… - Proteomes, 2022 - mdpi.com
It is thought that accurate risk assessment and early diagnosis of breast cancer (BC) can
help reduce cancer-related mortality. Proteomics analysis of breast milk may provide …

The last universal common ancestor of ribosome-encoding organisms: portrait of LUCA

P Forterre - Journal of Molecular Evolution, 2024 - Springer
The existence of LUCA in the distant past is the logical consequence of the binary
mechanism of cell division. The biosphere in which LUCA and contemporaries were living …

Extracellular vesicles from uterine aspirates represent a promising source for screening markers of gynecologic cancers

GO Skryabin, AV Komelkov, KI Zhordania, DV Bagrov… - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs), including exosomes, are key factors of intercellular
communication, performing both local and distant transfers of bioactive molecules. The …

[HTML][HTML] Integrated miRNA Profiling of Extracellular Vesicles from Uterine Aspirates, Malignant Ascites and Primary-Cultured Ascites Cells for Ovarian Cancer …

GO Skryabin, AV Komelkov, KI Zhordania, DV Bagrov… - Pharmaceutics, 2024 - mdpi.com
Extracellular vesicles (EVs) are of growing interest in the context of screening for highly
informative cancer markers. We have previously shown that uterine aspirate EVs (UA EVs) …

Application of AFM, TEM, and NTA for characterization of exosomes produced by placenta-derived mesenchymal cells

DV Bagrov, AM Senkovenko, II Nikishin… - Journal of Physics …, 2021 - iopscience.iop.org
Exosomes and microvesicles usually require characterization at the single-particle level.
The most commonly used methods for this purpose are transmission electron microscopy …

[HTML][HTML] Plasma exosomal caveolin-1 predicts poor prognosis in ovarian cancer

L Yang, H Wu, Y Zhu, X Chen, Y Chen - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Objective: In this study, we aimed to evaluate the levels of plasma exosomal caveolin-1
(CAV1) and determine its prognostic value in ovarian cancer patients. Patients and Methods …

Optical imaging of single extracellular vesicles: Recent progress and prospects

B Ma, L Li, Y Bao, L Yuan, S Liu, L Qi… - … & Biomedical Imaging, 2023 - ACS Publications
Extracellular vesicles (EVs) are small, membrane-bound structures released by various cell
types into the extracellular environment, which play a crucial role in intercellular …

Isolation and characterization of extracellular vesicles from gastric juice

GO Skryabin, SV Vinokurova, SA Galetsky, DS Elkin… - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer (GC) is one of the most common cancers and the fifth
leading cause of cancer-related deaths worldwide. The steadily growing interest in secreted …