Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

Arginine and endothelial function

J Gambardella, W Khondkar, MB Morelli, X Wang… - Biomedicines, 2020 - mdpi.com
Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single …

M Tosato, R Calvani, A Picca, F Ciciarello, V Galluzzo… - Nutrients, 2022 - mdpi.com
Long COVID, a condition characterized by symptom and/or sign persistence following an
acute COVID-19 episode, is associated with reduced physical performance and endothelial …

Tripartite combination of candidate pandemic mitigation agents: vitamin D, quercetin, and estradiol manifest properties of medicinal agents for targeted mitigation of …

GV Glinsky - Biomedicines, 2020 - mdpi.com
Genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed
as baits to build genomic-guided molecular maps of upstream regulatory elements, their …

Heparan sulfate proteoglycans as attachment factor for SARS-CoV-2

L Liu, P Chopra, X Li, KM Bouwman… - ACS Central …, 2021 - ACS Publications
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) is causing an
unprecedented global pandemic demanding the urgent development of therapeutic …

Macrothrombosis and stroke in patients with mild Covid‐19 infection

MG Fara, LK Stein, M Skliut, S Morgello… - … of Thrombosis and …, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a pandemic disease currently affecting
millions of people worldwide. Its neurological implications are poorly understood, and further …

[HTML][HTML] Is COVID-19 associated thrombosis caused by overactivation of the complement cascade? A literature review

A Fletcher-Sandersjöö, BM Bellander - Thrombosis research, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 is responsible for the current COVID-19
pandemic resulting in an escalating number of cases and fatalities worldwide. Preliminary …

COVID-19 causes ferroptosis and oxidative stress in human endothelial cells

SS Jankauskas, U Kansakar, C Sardu, F Varzideh… - Antioxidants, 2023 - mdpi.com
Oxidative stress and endothelial dysfunction have been shown to play crucial roles in the
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …

Endothelial dysfunction and its clinical implications

P Poredos, AV Poredos, I Gregoric - Angiology, 2021 - journals.sagepub.com
Endothelial dysfunction (ED) plays a substantial role in the pathogenesis of atherosclerosis
and some other vascular diseases. ED has been demonstrated in patients with …

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2–implications for microvascular inflammation and hypercoagulopathy in COVID-19 patients

L He, MA Mäe, Y Sun, L Muhl, K Nahar, EV Liébanas… - BioRxiv, 2020 - biorxiv.org
Accumulating clinical observations suggest pathogenesis beyond viral pneumonia and its
secondary consequences in COVID-19 patients. In particular, many patients develop …