Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

P Suravajhala, LJA Kogelman… - Genetics Selection …, 2016 - Springer
In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

Factors affecting puberty in replacement beef heifers

GA Perry - Theriogenology, 2016 - Elsevier
Puberty is defined as when ovulation is accompanied by visual signs of estrus and
subsequent normal luteal function. Age at puberty is an important trait in relation to …

Multi-tissue omics analyses reveal molecular regulatory networks for puberty in composite beef cattle

A Cánovas, A Reverter, KL DeAtley, RL Ashley… - PloS one, 2014 - journals.plos.org
Puberty is a complex physiological event by which animals mature into an adult capable of
sexual reproduction. In order to enhance our understanding of the genes and regulatory …

The development and application of genomic selection as a new breeding paradigm

A Eggen - Animal frontiers, 2012 - academic.oup.com
A significant gap exists between demand based on population growth and the current
trajectory of yield; this is a point of leverage for genomics.• Although traditional breeding …

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

Z Cai, B Guldbrandtsen, MS Lund, G Sahana - BMC genomics, 2018 - Springer
Background Improving resistance to mastitis, one of the costliest diseases in dairy
production, has become an important objective in dairy cattle breeding. However, mastitis …

Prospecting major genes in dairy buffaloes

GMF De Camargo, RR Aspilcueta-Borquis, MRS Fortes… - BMC genomics, 2015 - Springer
Abstract Background Asian buffaloes (Bubalus bubalis) have an important socio-economic
role. The majority of the population is situated in developing countries. Due to the scarce …

A single nucleotide polymorphism-derived regulatory gene network underlying puberty in 2 tropical breeds of beef cattle

MRS Fortes, A Reverter, SH Nagaraj… - Journal of Animal …, 2011 - academic.oup.com
Harsh tropical environments impose serious challenges on poorly adapted species. In beef
cattle, tropical adaptation in the form of temperature and disease resistance, coupled with …

Genome‐wide association study reveals candidate genes associated with body measurement traits in Chinese Wagyu beef cattle

B An, J Xia, T Chang, X Wang, L Xu, L Zhang… - Animal …, 2019 - Wiley Online Library
We performed a genome‐wide association study to identify candidate genes for body
measurement traits in 463 Wagyu beef cattle typed with the Illumina Bovine HD 770K SNP …

A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine

M Gòdia, A Reverter, R González-Prendes… - Genetics Selection …, 2020 - Springer
Background Genetic pressure in animal breeding is sparking the interest of breeders for
selecting elite boars with higher sperm quality to optimize ejaculate doses and fertility rates …

A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle

P Widmann, A Reverter, MRS Fortes, R Weikard… - BMC genomics, 2013 - Springer
Background Systems biology enables the identification of gene networks that modulate
complex traits. Comprehensive metabolomic analyses provide innovative phenotypes that …