Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

Modulation of the biochemical composition of the tumour microenvironment is a new frontier
of cancer therapy. Several immunosuppressive mechanisms operate in the milieu of most …

The overlapping metabolic reprogramming of cancer and immune cells is a putative
determinant of the antitumor immune response in cancer. Increased evidence suggests that …

Activatable phototheranostics is highly appealing to meet the demand of precision medicine.
However, although it displays efficacy in the construction of activatable photosensitizers …

This review article provides a historical perspective on the role of purinergic signalling in the
regulation of various subsets of immune cells from early discoveries to current …

Emerging evidence has demonstrated that radiotherapy (RT) can not only cause direct
damage to cancer cells but also lead to immunogenic cell death (ICD), which involves the …

Abstract Extracellular adenosine 5′-triphosphate (ATP) and adenosine molecules are
intimately involved in immune responses. ATP is mostly a pro-inflammatory molecule and is …

Metabolic reprogramming and altered bioenergetics have emerged as hallmarks of cancer
and an area of active basic and translational cancer research. Drastically upregulated …