The global cognitive impairment in schizophrenia: consistent over decades and around the world

J Schaefer, E Giangrande, DR Weinberger… - Schizophrenia …, 2013 - Elsevier
Objective Schizophrenia results in cognitive impairments as well as positive, negative, and
disorganized symptomatology. The present study examines the extent to which these …

Characterising the structure of cognitive heterogeneity in schizophrenia spectrum disorders. A systematic review and narrative synthesis

SP Carruthers, TE Van Rheenen, C Gurvich… - Neuroscience & …, 2019 - Elsevier
The aim of the present review was to systematically summarise our current understanding of
the structure of the cognitive heterogeneity that exists within schizophrenia spectrum …

[HTML][HTML] Multivariate neuroanatomical classification of cognitive subtypes in schizophrenia: a support vector machine learning approach

IC Gould, AM Shepherd, KR Laurens, MJ Cairns… - NeuroImage: Clinical, 2014 - Elsevier
Heterogeneity in the structural brain abnormalities associated with schizophrenia has made
identification of reliable neuroanatomical markers of the disease difficult. The use of more …

[HTML][HTML] The impact of premorbid and current intellect in schizophrenia: cognitive, symptom, and functional outcomes

R Wells, V Swaminathan, S Sundram, D Weinberg… - npj …, 2015 - nature.com
Background: Cognitive heterogeneity among people with schizophrenia has been defined
on the basis of premorbid and current intelligence quotient (IQ) estimates. In a relatively …

Characterising demographic, clinical and functional features of cognitive subgroups in schizophrenia spectrum disorders: a systematic review

SP Carruthers, TE Van Rheenen, JA Karantonis… - Neuropsychology …, 2022 - Springer
Considerable cognitive heterogeneity is present within the schizophrenia spectrum disorder
(SSD) population. Several subgroups characterised by more homogenous cognitive profiles …

Cluster analysis of cognitive deficits may mark heterogeneity in schizophrenia in terms of outcome and response to treatment

E Gilbert, C Mérette, V Jomphe, C Émond… - European archives of …, 2014 - Springer
Cognitive impairments are central to schizophrenia, but their clinical utility for tagging
heterogeneity in lifetime outcome and response to treatment is not conclusive. By exploiting …

[HTML][HTML] Brain morphological characteristics of cognitive subgroups of schizophrenia-spectrum disorders and bipolar disorder: A systematic review with narrative …

JA Karantonis, SP Carruthers, KE Burdick… - Neuropsychology …, 2023 - Springer
Despite a growing body of research, there is yet to be a cohesive synthesis of studies
examining differences in brain morphology according to patterns of cognitive function …

Cognitive heterogeneity in first-episode psychosis and its relationship with premorbid developmental adjustment

EJ Tan, SL Rossell, KL Subotnik, J Ventura… - Psychological …, 2022 - cambridge.org
Background Patients with schizophrenia spectrum disorders have been increasingly
recognised to form cognitive subgroups with differential levels of impairment. Using cluster …

[HTML][HTML] Domain-specific cognitive course in schizophrenia: Group-and individual-level changes over 10 years

CB Flaaten, I Melle, T Bjella, MJ Engen, G Åsbø… - Schizophrenia Research …, 2022 - Elsevier
Cognitive impairments in schizophrenia are well-documented, present across several
cognitive domains and found to be relatively stable over time. However, there is a high …

Parcellating cognitive heterogeneity in early psychosis-spectrum illnesses: a cluster analysis

JJ Crouse, AA Moustafa, SER Bogaty, IB Hickie… - Schizophrenia …, 2018 - Elsevier
Cognitive impairment is argued to represent a core feature of psychosis-spectrum illnesses.
However, within-diagnosis heterogeneity is common, and risk factors for poor cognition …