GPCR signaling and cardiac function

LA Capote, RM Perez, A Lymperopoulos - European journal of …, 2015 - Elsevier
G protein-coupled receptors (GPCRs), such as β-adrenergic and angiotensin II receptors,
located in the membranes of all three major cardiac cell types, ie myocytes, fibroblasts and …

Antifibrotic therapies to control cardiac fibrosis

Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …

Peripartum cardiomyopathy: an update

F Azibani, K Sliwa - Current heart failure reports, 2018 - Springer
Abstract Purpose of Review Peripartum cardiomyopathy (PPCM) is an idiopathic disorder
defined as heart failure occurring in women during the last month of pregnancy and up to 5 …

Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver

HK Awada, MP Hwang, Y Wang - Biomaterials, 2016 - Elsevier
Ischemic heart disease is a leading cause of death worldwide. After the onset of myocardial
infarction, many pathological changes take place and progress the disease towards heart …

Relaxin-2 and soluble Flt1 levels in peripartum cardiomyopathy: results of the multicenter IPAC study

J Damp, MM Givertz, M Semigran, R Alharethi… - JACC: Heart Failure, 2016 - jacc.org
Objectives: This study explored the association of vascular hormones with myocardial
recovery and clinical outcomes in peripartum cardiomyopathy (PPCM). Background: PPCM …

Nephrotic syndrome: oedema formation and its treatment with diuretics

S Gupta, RJ Pepper, N Ashman, SB Walsh - Frontiers in physiology, 2019 - frontiersin.org
Oedema is a defining element of the nephrotic syndrome. Its' management varies
considerably between clinicians, with no national or international clinical guidelines, and …

Intraarticular injection of relaxin-2 alleviates shoulder arthrofibrosis

WA Blessing, SM Okajima, MB Cubria… - Proceedings of the …, 2019 - National Acad Sciences
Arthrofibrosis is a prevalent condition affecting greater than 5% of the general population
and leads to a painful decrease in joint range of motion (ROM) and loss of independence …

Mechanisms and management of edema in pediatric nephrotic syndrome

M Kallash, JD Mahan - Pediatric nephrology, 2021 - Springer
Edema is the abnormal accumulation of fluid in the interstitial compartment of tissues within
the body. In nephrotic syndrome, edema is often seen in dependent areas such as the legs …

Anthracycline and peripartum cardiomyopathies: Predictably unpredictable

JA Cowgill, SA Francis, DB Sawyer - Circulation research, 2019 - Am Heart Assoc
Anthracycline-associated cardiomyopathy and peripartum cardiomyopathy are nonischemic
cardiomyopathies that often afflict previously healthy young patients; both diseases have …

Peripartum cardiomyopathy

N Jha, AK Jha - Heart Failure Reviews, 2021 - Springer
Peripartum cardiomyopathy is now increasingly recognized as a cause of heart failure in the
later months of pregnancy and early postpartum period. Clinical diagnosis may be …