Background: Chronic diseases such as diabetes have an adverse effect on the quality of life
(QOL) of patients. It has been shown physical activity can improve the quality of life. Aims …

Adipose tissue is a major source of energy for the human body. It is also a source of major
adipocytokines adiponectin and leptin. Insulin resistance is a condition in which insulin …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

There has been much effort recently to define the role of adipocytokines, which are soluble
mediators derived mainly from adipocytes (fat cells), in the interaction between adipose …

A growing number of extreme climate events are occurring in the setting of ongoing climate
change, with an increase in both the intensity and frequency. It has been shown that ambient …

The dramatic increase in the prevalence of obesity and its strong association with
cardiovascular disease have resulted in unprecedented interest in understanding the effects …

Cardiovascular disease (CVD) is the greatest cause of death, accounting for nearly one-third
of all deaths worldwide. The increase in obesity rates over 3 decades is widespread and …

Almost 20 years have passed since the first laboratory evidence emerged that an abundant
message encoding a protein with homology to the C1q superfamily is highly specifically …

Secreted polypeptides are a fundamental axis of intercellular and endocrine communication.
However, a global understanding of the composition and dynamics of cellular secretomes in …