Genomic instability consists of a range of genetic alterations within the genome that contributes to tumor heterogeneity and drug resistance. It is a well-established characteristic …
M Iyer, U Anand, S Thiruvenkataswamy… - Science of the Total …, 2023 - Elsevier
Carcinogenic metals affect a variety of cellular processes, causing oxidative stress and cancer. The widespread distribution of these metals caused by industrial, residential …
Z Jiang, R Person, T Lundh, D Pineda, M Engfeldt… - Environment …, 2024 - Elsevier
Abstract Background Hexavalent chromium (Cr (Ⅵ)) is classified as a group 1 human carcinogen and increases the risk of lung cancer. Non-coding RNAs (ncRNAs) have key …
L Wang, LZ Liu, BH Jiang - Seminars in cancer biology, 2021 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding RNAs that regulate cancer initiation, development, angiogenesis, and therapeutic resistance. Metal exposure widely …
L Wang, K Bayanbold, L Zhao, Y Wang… - Science of the Total …, 2022 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a well-known carcinogen that can cause several types of cancer including lung cancer. NF-E2-related factor 2 (Nrf2), the redox sensitive …
S Hong, Z Su, Y Zhang, G Hu, Q Zhang… - Environmental …, 2024 - ACS Publications
Genotoxic and immunosuppressive characteristics are central to the carcinogenic profile of hexavalent chromium [Cr (VI)], with dysregulation of circulating exosomal miRNA potentially …
Background Trivalent chromium is a trace element thought to have a beneficial effect on oxidative stress (OS) parameters and inflammation. This review aimed to investigate the …
Z Wang, C Yang - Advances in Pharmacology, 2023 - Elsevier
Abstract Hexavalent chromium [Cr (VI)], a Group I carcinogen classified by the International Agency for Research on Cancer (IARC), represents one of the most common occupational …
Heavy metals in its various ionic forms present beyond the tolerable limits are considered to be toxic for human use and environment. One such primary pollutant metal is hexavalent …