Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of
intestinal, respiratory, and urogenital mucosal epithelia separating the outside environment …

Prevention of infections by vaccination remains a compelling goal to improve public health.
Mucosal vaccines would make immunization procedures easier, be better suited for mass …

Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million
new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …

Breastfeeding protects the neonate against pathogen infection. Major mechanisms of
protection include human milk glycoconjugates functioning as soluble receptor mimetics that …

Vaccines have been traditionally developed with the presumption that they exert identical
immunogenicity regardless of target population and that they provide protection solely …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is still a major threat to
mankind, urgently requiring improved vaccination and therapeutic strategies to reduce TB …

Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (Mtb).
Whilst a functional role for humoral immunity in Mtb protection remains poorly defined …

Currently, there is a trend of increasing incidence in pulmonary non-tuberculous
mycobacterial infections (PNTM) together with a decrease in tuberculosis (TB) incidence …

Tuberculosis (TB) is a serious public health problem worldwide. The combination of various
anti-TB drugs is mainly used to treat TB in clinical practice. Despite the availability of …

Induction of specific humoral and cellular immunity in the lung airways is proposed to be
critical for vaccine protection against Mycobacterium tuberculosis (M. tb). To facilitate airway …