The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets

S Baroni, T Carletti, M Donalisio, I Arduino… - Frontiers in Cellular …, 2024 - frontiersin.org
Coronaviruses (CoVs) share key genomic elements critical for viral replication, suggesting
the feasibility of developing therapeutics with efficacy across different viruses. In a previous …

Antimicrobial Efficacy of a Vegetable Oil Plasticizer in PVC Matrices

G Bajetto, S Scutera, F Menotti, G Banche, G Chiaradia… - Polymers, 2024 - mdpi.com
The growing prevalence of bacterial and viral infections, highlighted by the recent COVID-19
pandemic, urgently calls for new antimicrobial strategies. To this end, we have synthesized …

Antiherpetic Activity of a Root Exudate from Solanum lycopersicum

G Bajetto, D Arnodo, M Biolatti, L Trifirò, C Albano… - Microorganisms, 2024 - mdpi.com
The rise of drug resistance to antivirals poses a significant global concern for public health;
therefore, there is a pressing need to identify novel compounds that can effectively …

New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors

A Messore, P Malune, E Patacchini, VN Madia… - Pharmaceuticals, 2024 - mdpi.com
It has been more than four years since the first report of SARS-CoV-2, and humankind has
experienced a pandemic with an unprecedented impact. Moreover, the new variants have …

[HTML][HTML] Lycorine derivative effectively inhibits the replication of coronaviruses both in vitro and in vivo

L Shen, J Zhao, Y Xia, J Lu, J Sun, J Tang, H Xing… - hLife, 2024 - Elsevier
The established and ongoing prevalence of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) and seasonal human coronaviruses (HCoV) like HCoV-OC43, HCoV …