Exploring the use of animal models in craniofacial regenerative medicine: a narrative review

SA Mosaddad, A Hussain… - Tissue Engineering Part B …, 2024 - liebertpub.com
The craniofacial region contains skin, bones, cartilage, the temporomandibular joint (TMJ),
teeth, periodontal tissues, mucosa, salivary glands, muscles, nerves, and blood vessels …

Mechanisms of pathological scarring: role of myofibroblasts and current developments

V Sarrazy, F Billet, L Micallef, B Coulomb… - Wound Repair and …, 2011 - Wiley Online Library
Myofibroblasts play a key role in the wound‐healing process, promoting wound closure and
matrix deposition. These cells normally disappear from granulation tissue by apoptosis after …

Physical management of scar tissue: a systematic review and meta-analysis

C Deflorin, E Hohenauer, R Stoop… - The journal of …, 2020 - liebertpub.com
Objective: The aim of this systematic review with meta-analysis was to describe the status on
the effects of physical scar treatments on pain, pigmentation, pliability, pruritus, scar …

The practical utility of psychometric scales for the assessment of the impact of posttraumatic scars on mental health

GM Mekereș, CL Buhaș, C Tudoran… - Frontiers in Public …, 2023 - frontiersin.org
Background Scars are a natural consequence of the healing process, but with an impact on
the psychological and social level for the individual, which can even lead to withdrawal and …

Vascular and collagen target: a rational approach to hypertrophic scar management

B Yuan, Z Upton, D Leavesley, C Fan… - Advances in Wound …, 2023 - liebertpub.com
Significance: Hypertrophic scarring is a challenging issue for patients and clinicians. The
prevalence of hypertrophic scarring can be up to 70% after burns, and patients suffer from …

Discovery of a novel short peptide with efficacy in accelerating the healing of skin wounds

Y Wang, Z Feng, M Yang, L Zeng, S Yin, B Li, Y Li… - Pharmacological …, 2021 - Elsevier
Despite extensive efforts to develop efficacious therapeutic approaches, the treatment of
skin wounds remains a considerable clinical challenge. Existing remedies cannot sufficiently …

Impaired Notch‐MKP‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology

BC Melnik, G Plewig - Experimental dermatology, 2013 - Wiley Online Library
Recent findings in familial hidradenitis suppurativa (HS) demonstrated loss‐of‐function
mutations of components of the γ‐secretase (GS) complex leading to decreased protease …

Optimal treatment of partial thickness burns in children: a systematic review

A Vloemans, MHE Hermans, MBA Van Der Wal… - Burns, 2014 - Elsevier
A large part of the patient population of a burn centre consists of children, most of whom are
younger than four years. The majority of these young children suffer from superficial and …

[HTML][HTML] Inflammation as an orchestrator of cutaneous scar formation: A review of the literature

TA Wilgus - Plastic and aesthetic research, 2020 - ncbi.nlm.nih.gov
Inflammation is a key phase in the cutaneous wound repair process. The activation of
inflammatory cells is critical for preventing infection in contaminated wounds and results in …

Current and emerging treatments for postsurgical cleft lip scarring: effectiveness and mechanisms

E Papathanasiou, CA Trotman… - Journal of dental …, 2017 - journals.sagepub.com
Cleft lip with or without cleft palate is the most common congenital malformation of the head
and the third-most common birth defect. Surgical repair of the lip is the only treatment and is …