Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Mechanical damage is one of the predisposing factors of inflammation, and it runs through
the entire inflammatory pathological process. Repeated or persistent damaging mechanical …

Alzheimer's disease (AD) is the most common neurodegenerative disease illustrated by
neuronal dysfunctions, leading to memory weaknesses and personality changes mostly in …

This narrative review summarises the evidence for considering physical exercise (PE) as a
non-pharmacological intervention for delaying cognitive decline in patients with Alzheimer's …

Traumatic brain injury (TBI) signifies a major cause of death and disability. TBI causes
central nervous system (CNS) damage under a variety of mechanisms, including protein …

O-cyclic phytosphingosine-1-phosphate (cPS1P) is a novel and chemically synthesized
sphingosine metabolite derived from phytosphingosine-1-phosphate (S1P). This study was …

Alzheimer's Disease (AD) remains a formidable challenge due to its complex pathology,
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …

Tyrosine-protein kinase (Syk) plays a potential role in neuroinflammation and adaptive
immune responses in several neurodegenerative conditions. Seeing the significant role of …

Oxidative stress plays an important role in cognitive dysfunctions and is seen in
neurodegeneration and Alzheimer's disease (AD). It has been reported that the polyphenolic …