There is an art and science to performing mouse anesthesia, which is a significant
component to animal research. Frequently, anesthesia is one vital step of many over the …

With the advent of transgenic and other genetic engineering technologies, the versatility and
usefulness of the mouse as a model in biomedical research has soared. Revised to reflect …

The order Rodentia is extraordinarily varied and diverse, with extensive ranges in
morphology, diet, activity, metabolism, and anatomy among its members. The order boasts …

Within the scope of the 3Rs of Russel and Burch, the number of laboratory animals can be
reduced by repeated use of an animal. This strategy only becomes relevant, if the total …

Oxygen supplementation is rarely considered when anesthetizing laboratory mice, despite
reports that mice become profoundly hypoxic under anesthesia. Little is known about the …

Since its recent reformulation, alfaxalone has gained popularity as an injectable veterinary
anesthetic, including promising studies demonstrating the use of alfaxalone–xylazine for …

Trypanosoma cruzi is the causal agent of Chagas disease, a parasitic zoonosis transmitted
mainly through the feces of triatomine insects. Triatoma infestans is the main triatomine …

Background The role of miR-23b-3p in insulin resistance (IR) remained poorly understood.
Methods After acacetin injection, obesity-induced IR model was constructed with or without …

Simple Summary We studied the locomotor activity of one of the kissing bug species that
transmit the Chagas disease-causing parasite in humans, which usually bites during the …

Geriatric animal models are crucial for a better understanding and an improved therapy of
age-related diseases. We observed a high mortality of aged mice after anesthesia with a …