[HTML][HTML] Exploitation of glycosylation in enveloped virus pathobiology
Y Watanabe, TA Bowden, IA Wilson… - Biochimica et Biophysica …, 2019 - Elsevier
Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
Recent progress in broadly neutralizing antibodies to HIV
D Sok, DR Burton - Nature immunology, 2018 - nature.com
In this Review, we highlight some recent developments in the discovery and application of
broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV); ie …
broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV); ie …
[HTML][HTML] Molecular architecture of the SARS-CoV-2 virus
H Yao, Y Song, Y Chen, N Wu, J Xu, C Sun, J Zhang… - Cell, 2020 - cell.com
SARS-CoV-2 is an enveloped virus responsible for the COVID-19 pandemic. Despite recent
advances in the structural elucidation of SARS-CoV-2 proteins, the detailed architecture of …
advances in the structural elucidation of SARS-CoV-2 proteins, the detailed architecture of …
Site-specific glycan analysis of the SARS-CoV-2 spike
The emergence of the betacoronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
Pre-existing immunity to seasonal endemic coronaviruses could have profound
consequences for antibody responses to SARS-CoV-2, induced from natural infection or …
consequences for antibody responses to SARS-CoV-2, induced from natural infection or …
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
[HTML][HTML] Unexpected receptor functional mimicry elucidates activation of coronavirus fusion
Recent outbreaks of severe acute respiratory syndrome and Middle East respiratory
syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the …
syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the …
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
Broadly neutralizing antibodies (bnAbs) to coronaviruses (CoVs) are valuable in their own
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
Native-like SARS-CoV-2 spike glycoprotein expressed by ChAdOx1 nCoV-19/AZD1222 vaccine
Vaccine development against the SARS-CoV-2 virus focuses on the principal target of the
neutralizing immune response, the spike (S) glycoprotein. Adenovirus-vectored vaccines …
neutralizing immune response, the spike (S) glycoprotein. Adenovirus-vectored vaccines …
Virus-receptor interactions of glycosylated SARS-CoV-2 spike and human ACE2 receptor
The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …