RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …

Progress in the design of G-quadruplex (G4) binding ligands relies on the availability of
approaches that assess the binding mode and nature of the interactions between G4 …

G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with
the potential to form G4s are abundant in regulatory regions of the genome including …

Abstract The Epstein-Barr virus (EBV) is the first oncogenic virus described in human. EBV
infects more than 90% of the human population worldwide, but most EBV infections are …

The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

Summary G-quadruplexes (G4s) are stable, noncanonical structures formed in guanine (G)-
rich sequences of DNA/RNA. G4 structures are reported to play a regulatory role in various …

Abstract RNA G-quadruplexes (rG4) have recently emerged as major regulatory elements in
both mRNA and non-coding RNA. In order to investigate the biological roles of rG4 …

The development of triple-negative breast cancer (TNBC) is highly associated with G-
quadruplex (G4); thus, targeting G4 is a potential strategy for TNBC therapy. Because …

RNA G-quadruplexes (rG4s) are non-canonical secondary structures that are formed by the
self-association of guanine quartets and that are stabilized by monovalent cations (eg …

Abstract G-quadruplexes (G4) are 3D structures that are found in both DNA and RNA.
Interest in this structure has grown over the past few years due to both its implication in …