Programmed death of intestinal epithelial cells in neonatal necrotizing enterocolitis: a mini-review

S Yang, X Wei, Y Zhong, C Guo, X Liu, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Necrotizing enterocolitis (NEC) is one of the most fatal diseases in premature infants.
Damage to the intestinal epithelial barrier (IEB) is an important event in the development of …

[HTML][HTML] A novel role for necroptosis in the pathogenesis of necrotizing enterocolitis

AD Werts, WB Fulton, MR Ladd, A Saad-Eldin… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …

Enteral feeding interventions in the prevention of necrotizing enterocolitis: a systematic review of experimental and clinical studies

IH de Lange, C van Gorp, LD Eeftinck Schattenkerk… - Nutrients, 2021 - mdpi.com
Necrotizing enterocolitis (NEC), which is characterized by severe intestinal inflammation and
in advanced stages necrosis, is a gastrointestinal emergency in the neonate with high …

Let-7d-5p suppresses inflammatory response in neonatal rats with necrotizing enterocolitis via LGALS3-mediated TLR4/NF-κB signaling pathway

L Sun, M Sun, K Ma, J Liu - American Journal of Physiology …, 2020 - journals.physiology.org
Necrotizing enterocolitis (NEC) is an acute intestinal condition accounting for severe
mortality and morbidity in preterm infants. This study aimed to identify the possible roles of …

How does human milk protect against necrotizing enterocolitis (NEC)? Targeted validation and time-course analysis of 35 gene responses as NEC-signature in fetal …

C Tongviratskool, N Pongsakul… - OMICS: A Journal of …, 2022 - liebertpub.com
Breastfeeding reduces the risk of necrotizing enterocolitis (NEC), one of the most common
causes of morbidity and mortality in preterm infants. However, the molecular substrates by …

Protective Effect of γ-mangostin Isolated from the Peel of Garcinia mangostana against Glutamate-Induced Cytotoxicity in HT22 Hippocampal Neuronal Cells

JY Baek, K Jung, YM Kim, HY Kim, KS Kang, YW Chin - Biomolecules, 2021 - mdpi.com
The aim of the present study was to examine the protective effect of γ-mangostin, a
component of the mangosteen shell, against oxidative damage to nerve cells induced by …

FTY720 attenuates intestinal injury and suppresses inflammation in experimental necrotizing enterocolitis via modulating CXCL5/CXCR2 axis

Z Feng, H Zhou, S Ma, X Guan, L Chen, J Huang… - Biochemical and …, 2018 - Elsevier
Necrotizing enterocolitis (NEC) remains one of the leading causes of death in neonatal
infants and new therapeutic strategies for NEC are urgently required. The …

Diallyl trisulfide plays an antifibrotic role by inhibiting the expression of Bcl‐2 in hepatic stellate cells

H Pang, C Wang, J Ye, L Wang, X Zhou… - … of Biochemical and …, 2022 - Wiley Online Library
Hepatic fibrosis is an important early stage in the evolution of liver cirrhosis, and specific
medicine and therapeutic measures are unavailable to date. Hepatic stellate cells (HSCs) …

Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells

K Lin, R Yang, Z Zheng, Y Zhou, Y Geng, Y Hu… - Cell Death …, 2017 - nature.com
Sulforaphane (SFN) was demonstrated to induce apoptosis in a variety of cancers via
multiple mechanisms. However, owing to a short half-life in circulation, SFN was not used for …

Intestinal tract and parenteral multi-organ sequential pathological injury caused by necrotizing enterocolitis

FS Wang, ML Yu, WZ Li, K Hong, CB Xu, GH Wang - BMC pediatrics, 2020 - Springer
Background To explore the relationship between the pathological changes of the colon,
terminal ileum, lung, liver and kidney, and the changes of Bax, PCNA and PAF in a rat model …