Several histopathological variants of colorectal carcinoma can be distinguished, some
associated with specific molecular profiles. However, in routine practice, ninety/ninety-five …

Although tumor stage has a profound influence on prognosis, several histologic features are
also important. These parameters predict biological behavior and can be used by clinicians …

Aims The importance of the interaction between tumour cells and neutrophils has recently
begun to emerge. However, the significance of tumour-infiltrating neutrophil (TIN) in …

Aims Medullary carcinoma is an uncommon colorectal tumour which appears poorly
differentiated histologically. Consequently, it may be confused with poorly differentiated …

Background Young adults with metastatic colorectal cancer (mCRC) may have higher rates
of deficient mismatch repair (dMMR) than older patients. This study sought to assess …

Background We aimed to analyze the benefit of adjuvant chemotherapy in high-risk stage II
colon cancer patients and the impact of high-risk factors on the prognostic effect of adjuvant …

Background Gastric cancer with liver metastasis (GCLM) patients typically have a grim
prognosis and are at high risk of early mortality. This study aimed to predict cancer-specific …

DNA mismatch repair (MMR) proteins may play an important role in colorectal
carcinogenesis. In our study, the clinicopathological features of defective MMR in sporadic …

Background The liver is the most common site for rectal cancer metastasis, and liver
resection combined with chemotherapy is the only treatment offering the possibility of long …

Objective: KRAS and mismatch repair genes are two important molecular markers used in
determining prognosis and probability of response to the targeted therapy in patients with …