This review covers the recent developments (since 2015) of enantioselective
desymmetrization reactions using metal-catalyzed, organocatalyzed and enzymatic …

The catalytic asymmetric dearomatization (CADA) reaction has proved to be a powerful
protocol for rapid assembly of valuable three-dimensional cyclic compounds from readily …

Herein, we report a synthesis of cyclohexanones bearing multi‐continuous stereocenters by
combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to cyclic …

Dearomative reactions allow for concise assembly of structurally complex, highly
functionalized three‐dimensional molecules by breaking the plane of two‐dimensional …

Synthetic application of asymmetric catalysis relies on strategic alignment of bond
construction to creation of chirality of a target molecule. Remote desymmetrization offers …

Medium-sized rings are important structural units, but their synthesis, especially in a highly
enantioselective manner, has been a great challenge. Herein we report an enantioselective …

Para-selective C–H functionalization of free phenols by metal carbenoids is rather
challenging due to the generally more favorable competing O–H insertion. Herein, with the …

Pd-catalyzed intermolecular asymmetric allylic dearomatization of substituted β-naphthol
derivatives with Boc-protected Morita–Baylis–Hillman (MBH) adducts was developed. The …

An organocatalytic asymmetric construction of hexahydropyrrolo [2, 3-b] indole-containing
tetrasubstituted allene scaffolds bearing both axial chirality and central chirality has been …

Reported herein is the catalytic asymmetric aminative dearomatization reaction of common
phenols. As opposed to the well-studied indoles and naphthols, phenols are supposed to be …