A review of bisindolylmethane as an important scaffold for drug discovery

S Imran, M Taha… - Current Medicinal …, 2015 - ingentaconnect.com
Bisindolylmethane and its derivatives are pharmacologically active and applicable in the
field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities …

p-Toluenesulfonic acid-promoted organic transformations for the generation of molecular complexity

S Pal, D Das, S Bhunia - Organic & Biomolecular Chemistry, 2024 - pubs.rsc.org
Since the beginning of this century, p-toluenesulfonic acid (p-TSA) catalyzed organic
transformations have been an active area of research in pursuit of developing efficient …

Hydrogen‐Bonding‐Assisted Cationic Aqua Palladium (II) Complex Enables Highly Efficient Asymmetric Reactions in Water

T Kitanosono, T Hisada, Y Yamashita… - Angewandte …, 2021 - Wiley Online Library
Metal‐bound water molecules have recently been recognized as a new facet of soft Lewis
acid catalysis. Herein, a chiral palladium aqua complex was constructed that enables …

Regioselective 2-alkylation of indoles with α-bromo esters catalyzed by Pd/P, P= O system

W Tian, B Li, D Tian, W Tang - Chinese Chemical Letters, 2022 - Elsevier
A palladium-catalyzed 2-alkylation of indoles with α-bromo esters is developed by
employing a P, P= O ligand. The method features excellent regioselectivities, mild reaction …

Surfactant-Aided Chiral Palladium (II) Catalysis Exerted Exclusively in Water for the C–H Functionalization of Indoles

T Kitanosono, M Miyo, S Kobayashi - ACS Sustainable Chemistry …, 2016 - ACS Publications
The electrophilic palladation of indoles through C–H bond functionalization with the aid of
surfactant was achieved in water in a highly enantioselective manner. The system displayed …

Effect of N-heterocyclic carbene in palladium–tin heterobimetallic catalysis: a DFT supported study on the C3–H functionalization of unprotected indoles

MK Nayak, RR Maharana, A Mohanty… - Catalysis Science & …, 2024 - pubs.rsc.org
A new N-heterocyclic carbene (NHC)-based Pd–Sn heterobimetallic complex [(NHC) Pd (μ-
Br) SnCl3] 2 with low steric crowding in the active catalytic region was designed. The …

[HTML][HTML] Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis (indolyl) methanes

SS Mohapatra, ZE Wilson, S Roy, SV Ley - Tetrahedron, 2017 - Elsevier
Flow chemistry enables the preparation of bis (indolyl) methanes from various indoles and
structurally divergent aldehydes using Sc (OTf) 3 catalysis. The reaction is regioselective for …

Lemon juice mediated efficient and eco-friendly organic transformations

D Das - Tetrahedron Letters, 2020 - Elsevier
Lemon juice has been extensively explored recently as highly selective and efficient
biocatalyst as well as green solvent in organic synthesis. Lemon juice holds considerable …

Iron‐containing ionic liquid as an efficient and recyclable catalyst for the synthesis of C3‐substituted indole derivatives

YC Gu, RM Hu, MM Li, DZ Xu - Applied Organometallic …, 2019 - Wiley Online Library
A facile and efficient protocol for the synthesis of C3‐substituted indole derivatives has been
developed under mild condition. The iron‐containing ionic liquid, 1‐(2‐hydroxyethyl)‐1, 4 …

A Tandem Hydroformylation‐Organocatalyzed Friedel‐Crafts Reaction for the Synthesis of Diindolylmethanes

L Miller, F Bauer, B Breit - Chemistry–A European Journal, 2024 - Wiley Online Library
Herein, we present an efficient and atom‐economic tandem hydroformylation
organocatalyzed Friedel‐Crafts reaction sequence for the synthesis of diindolylmethanes …