Circular RNAs (circRNAs) are connected at the 3′ and 5′ ends by exon or intron
cyclization, forming a complete ring structure. circRNA is more stable and conservative than …

Circular RNAs (circRNAs) are long, non-coding RNAs that result from the non-canonical
splicing of linear pre-mRNAs. However, the characteristics and the critical role of circRNA in …

Circular RNAs (circRNAs) are a class of non-coding RNAs that do not have 5′ end caps or
3′ end poly (A) tails. There are more than one hundred thousand genes that encode …

Background Ovarian cancer is the most lethal gynecologic cancer and the fifth leading
cause of cancer-related mortality in women worldwide. Despite various attempts to improve …

Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

Background Pancreatic ductal adenocarcinoma (PDAC) is the most deadly type of tumor,
and its pathogenesis remains unknown. Circular RNAs (circRNAs) may be functional and …

MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …

Silicosis is one of the typical forms of pneumoconiosis characterized by abnormal
proliferation of fibroblasts and deposition of extracellular matrix. Recent findings have shown …

Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic
pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic …

Epithelial-to-mesenchymal transition (EMT) is a physiological process that is vital throughout
the human lifespan. In addition to contributing to the development of various tissues within …