Background Ferroptosis is essential to regulate tumor growth and serves as a promising
therapeutic target to lung cancer. Ubiquitin‐specific protease 35 (USP35) belongs to the …

This study was focused on the synthesis of new pyrimidines 4a, b, 5a, b and pyrazoles 6a, b
as ATP mimicking tyrosine kinase inhibitors of the epidermal growth factor receptor (EGFR) …

Ferroptosis is a newly described regulated form of cell death that contributes to the
progression of non-small cell lung cancers (NSCLCs). MicroRNA-302a-3p (miR-302a-3p) …

Background: Exosomes are cell-derived vesicles and bear a specific set of nucleic acids
including DNA (exoDNA). Thus, this study is to explore whether exoDNA in malignant …

Biomarkers such as clinical characteristics and laboratory indices have been widely used in
many respiratory diseases, such as chronic airway diseases, lung infection, lung cancer and …

Lung carcinoma is the most frequently diagnosed malignant neoplasms and mainly consists
of small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC). Large …

A new series of pyridothienopyrimidine derivatives was designed and evaluated as
antimicrobial and anticancer agents. The target compounds were synthesized starting with 3 …

New series of hexahydroquinoline and fused quinoline derivatives were designed and
synthesized. The thirty seven new compounds were screened for in vitro antitumor activity …

Circulating tumor DNA (ctDNA) in plasma has been used as a biomarker for cancer
detection and outcome prediction. In this study, we collected the five precipitates (fractions 1 …

Objective This study aimed to identify the influential factors for the sensitivity of epidermal
growth factor receptor (EGFR) plasma test in non-small cell lung cancer (NSCLC). The …